Essential to Life ENZYMES
CharactericASE of Enzymes “Traffic Cops” that keep everything regulated (homeostasis) Chemically specific CATALYST : the rate of reactions by a million
How do enzymes work? Enzymes lower the amount of energy needed to reach the Activation Energy (Ea) Ea must be reached for any chemical reaction to occur Usually by kinetic energy Ea= faster reaction
Mechanism of Enzyme Action
Animation
Enzyme Action Mechanism Let’s review: -Substrate? -Active Site? -Induced-fit Model=Dan Koshland Substrate binding causes structural change yielding a perfect fit. - E + S E-S P + E
Enzyme on the Job Hexokinase and Glucose
CharactericASE of Enzymes Some enzymes are inactive until needed (digestive enzymes) Others are deactivated immediately after use (blood clotting) Reused Examples
Ground Rules for Success! Enzymes require stable pH to perform +/- 7 (pepsin is an exception) Maintained body temperature or else…….
Denatured!!
1. Animation on ENZYMES 2. Enzymes 3.Smartboard Presentation