Central pancreatectomy – a suitable surgical procedure for pancreatic metastases of other neoplasms? Traian Dumitrascu Andra Scarlat, Mihnea Ionescu, Irinel Popescu Center of General Surgery and Liver Transplantation Fundeni Clinical Institute Bucharest, Romania

Introduction Isolated pancreatic metastases of other neoplasms represent an uncommon pathology. Standard pancreatic resections represent the current approach for patients with resectable disease. However, the role of parenchyma-sparing pancreatectomies for such pathology is poorly investigated. Reddy S et al, Lancet Oncol, 2009; Adler H et al, EJSO, 2014

Introduction Central pancreatectomy is a parenchyma-sparing alternative resection to distal pancreatectomy, for benign and low malignant potential tumors located on the pancreatic isthmus and/ or body. Iacono C et al, Br J Surg, 2013; Dumitrascu T et al, J Transl Med Res, 2015

Introduction

Aim of the study To assess the oncological outcomes after central pancreatectomies for pancreatic metastases of other neoplasms.

Patients & Methods A literature search was performed in order to identify and extract the data of the patients with central pancreatectomies for pancreatic metastases of other neoplasms. The Kaplan-Meier curve was used to assess the long-term survival.

Results

Results Overall survival time 46 months Dumitrascu T et al, Chirurgia, 2008

Results Overall survival time 28 months Dumitrascu T et al, J Transl Med Res, 2015

Results Mean survival time = 99 months Central pancreatectomies for pancreatic metastases of other neoplasms Overall survival Mean survival time = 99 months

Crippa S et al, World J Surg, 2006; Reddy S et al, Lancet Oncol, 2009; Strobel (2009) 44 56.8% Crippa Crippa S et al, World J Surg, 2006; Reddy S et al, Lancet Oncol, 2009; Strobel O et al, Ann Surg Oncol, 2009

Kwak JH et al, Korean J Hepatobiliary Pancreat Surg, 2014

Bassi C et al, Br J Surg, 2003

Conclusion Although exceptionally performed, a central pancreatectomy appears to be an oncologically safe surgical procedure in selected patients with pancreatic metastases of other neoplasms of the pancreatic body and isthmus, with potentially better postoperative functional results.