Frontotemporal Dementia

Slides:

Advertisements

Similar presentations

Callie Chatterton.

Advertisements

Observations on Frontal Lobe Function Restlessness – animals with bilateral frontal lobe lesions move about consistently and aimlessly Indifference – such.

Human Neuropsychology,

Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings Central Nervous System (CNS)  CNS = Brain + spinal cord  Surface anatomy includes.

1. Which color represents the frontal lobe?. 2. Which color represents the occipital lobe?

Adult Neurogenic Language and Cognitive-Communicative Disorders Chapter 19

A 67-year-old male with behavioral and language problems

A framework for psychopathology

TRAUMATIC BRAIN INJURY: EPIDEMIOLOGY, ANATOMY AND PATHOPHYSIOLOGY

Cortical vs. subcortical loops. Lateral inhibition in striatum.

Central Nervous System (CNS) CNS –brain –spinal cord.

Central Nervous System Part 2 Cerebrum: lobes, functions, ventricles Specialization Areas Cerebral dominance Disorders.

Neuroscience Limbic System Dr. Michael P. Gillespie.

Background The physiology of the cerebral cortex is organized in hierarchical manner. The prefrontal cortex (PFC) constitutes the highest level of the.

Get out a sheet of paper and letter it A through E.

Brain Damage & Neuroplasticity. Etiology of Brain Damage Traumatic Brain Injury (TBI) Cerebrovascular Injury (CVI) Tumors Anoxia (e.g., near drowning,

The Human Brain. Cerebellum: Compares intended movements with what is actually happening. Constantly receiving input Damage to cerebellum called ataxia.

Many Brain Regions Are Involved in Processes of Attention Several cortical regions are associated with the source or control of attention. The lateral.

Basic Pattern of the Central Nervous System Spinal Cord – ______________________________ surrounded by a _ – Gray matter is surrounded by _ myelinated.

PP 03b-Gross anatomy, in more detail

Human Anatomy & Physiology FIFTH EDITION Elaine N. Marieb PowerPoint ® Lecture Slide Presentation by Vince Austin Copyright © 2003 Pearson Education, Inc.

CSD 2230 HUMAN COMMUNICATION DISORDERS Topic 6 Language Disorders Adult Disorders Traumatic Brain Injury Dementia.

Traumatic Brain Injury Dr.Shamekh M. El-Shamy. Traumatic Brain Injuries Definition: Definition: An insult to the brain, not of a degenerative or congenital.

Central Nervous system 1G.LUFUKUJA2/25/2016. Nervous system Divided –Central nervous system Brain & Spinal cord –Peripheral nervous system Cranial and.

BRAIN ORGANIZATION. Our Amazing Brain 3 parts Old/Reptilian Inner/Mammalian Newest/Primate.

MEMORY SYSTEMS IN THE BRAIN Some Gross Anatomy. The Human Brain saggital section at midline.

Cerebral Cortex 3. Visual-spatial Analysis Regions of cerebrum –Parietal association cortex Junction of P,T, and O lobes Most important –Parietal association.

Delusional misidentification syndromes (DMS) are a group of rare and varied disorders in which, in their typical form, the patient thinks that a particular.

The Brain. The Big Questions What do different parts of the brain do, and how do they work together?  Information flows through neighborhoods..  Different.

This is an umbrella term, not a disease in its own right. It is a term used for a large group of symptoms that adversely affect the brain and can be caused.

Introduction to Neuroanatomy and Terminology. Main Regions of the Nervous System Two Main Divisions –Central Nervous System –Peripheral Nervous System.

Direct motor pathway Corticospinal pathway.

Brain & Behavior อ. พญ. ปุณย์จารี วิริยโกศล ภาควิชาจิตเวชศาสตร์ คณะแพทยศาสตร์ มหาวิทยาลัยเชียงใหม่

AZRA NAHEED MEDICAL COLLEGE DR.TAYYABA AZHAR. THE LIMBIC SYSTEM The word “limbic” means “border.” Originally, the term “limbic” was used to describe the.

Fig. 1 The effects of modelling global volume for the analysis of PDD relative to controls. Atrophy in PDD shown (A) compensated for differences in head.

MOTIVATION/EMOTION and the FRONTAL LOBES

CEREBRAL BLOOD CIRCULATION

CEREBRAL BLOOD CIRCULATION

Physiology of Cerebral Cortex

Integrating Test Data with other Clinical Information

Traumatic Brain Injury

17.3 The Limbic System and Higher Mental Functions

Temporal Lobes and it’s functions

Brain Parts With Mnemonics.

III. What Are the Basic Brain Structures and Their Functions?

Zhejiang University Ling Shucai

Temporal associational cortex

THE BASAL GANGLIA: Neuroanatomy

EDUC 797 – Brain-Based Teaching & Learning

BRAIN ORGANIZATION By Heidi Hisrich.

Functional organization of the primary motor cortex Premotor cortex

The Behavioral Geography of the Brain

Lateralization and Specialty Areas

Functional Neuroanatomy: Frontal Lobes

Subcortical Neuroanatomy

LIMBIC SYSTEM. LIMBIC SYSTEM History Paul Broca ( ): 1878: “le grand lobe limbique” Refers to a ring of gray matter on the medial aspect.

Basal ganglia movement modulation

Limbic forebrain Domina Petric, MD

BRAIN ORGANIZATION.

Lateralization and Specialty Areas

Deep Brain Stimulation for Neurologic and Neuropsychiatric Disorders

Thalamus OBJECTIVES: At the end of this lecture you should understand:

MOTIVATION/EMOTION and the FRONTAL LOBES

Chapter 3 The Human Brain 2. Copyright © 2010 Pearson Education, Inc., Upper Saddle River, NJ All rights reserved.

THE BRAIN AND BEHAVIOR.

BRAIN ORGANIZATION By Heidi Hisrich.

Associational cortex introduction

Presentation transcript:

Frontotemporal Dementia Thomas G. Bowers, Ph.D. 11/24/2018

Frontal Lobes Executive functions Include attention, problem solving, hypothesis testing, social cognition and judgment Relatively recent evolutionary development Last structure to mature and develop (~25 years old) 11/24/2018

Pineas Gage 11/24/2018

Other Views of Gage 11/24/2018

Gages Actual Skull 11/24/2018

Impact of Frontal Lesion Gage’s behavior became socially very inappropriate Displayed consistently poor social judgment 11/24/2018

Basic Gross Anatomy Motor, Premotor and Prefrontal regions Many projections to premotor from other cortical regions Extensive limbic projections to the premotor region 11/24/2018

Frontal Organization From anterior 1. Prefrontal 2. Premotor 3. Motor 11/24/2018

Frontal Organization Prefrontal Does not receive any primary sensory input except olfactory stimuli Extensive projections from other cortical regions Extensive projections from the limbic system Reciprocating projections 11/24/2018

Frontal Organization Premotor Broca’s Area Critical convergence zone 11/24/2018

Frontal Organization Motor Linked with the premotor cortex, sensory cortex, and the basal ganglia Gives rise to pyramidal tacts that descend subcortically 11/24/2018

Frontal Organization Prefrontal – Limbic Links Includes amygdala, hippocampus, thalamus, temporal lobe pole Involves social processing as empathy, moral emotions, interpersonal judgment 11/24/2018

Frontal Organization Prefrontal – Subcortical Links Thalamofrontal Frontial-striatal Difficulties here can include disinhibition, perserveration, loss of motivation, attentional disorders, hemispatial neglect 11/24/2018

Vulnerable to Impairment Traumatic brain injury Axonal shearing, contusions, laceration, hemorrhage Stroke ACA, rostral aspects of MCA Aneurysm Neurodegenerative disease Pick’s Frontotemporal dementia 11/24/2018

Vulnerable to Impairment Psychiatric disorders Hydroencephalus Brain tumors Orbitofrontal meningioma 11/24/2018

Frontal Region is Vulnerable Frontal pole and anterior horn of the temporal lobe in particular are sensitive to lesions Coup injury Contrecoup Shearing injuries Small petechial hemorrhage 11/24/2018

Degenerative Disorders Pick’s Disease Atrophy has an affinity for the frontotemporal region Development of Pick’s bodies Frontotemporal dementia Not frequent, but 10% of degenerative dementias 11/24/2018