What Do We Know About LDL-C?

Hospital Discharges for Patients With CVD

Estimate of the Association of Genetically Raised LDL-C or HDL-C and Risk of MI Using Multiple Genetic Variants as Instruments

Effect of Lower LDL-C on the Risk of CHD Mediated by Genetic Polymorphism

Relationship Between Cumulative LDL-C Exposure and Age

Comparison of Recent Major Guidelines

NLA Recommendations

Relationship Between LDL-C Reduction and CHD Relative Risk

Effect on CHD Events of Lowering LDL-C

IMPROVE-IT Enrollment and Study Period

IMPROVE-IT Efficacy

ODYSSEY Long-Term Study LDL-C Reduction Over Time

ODYSSEY Long-Term Study MACE Outcomes

LDL-C Change: Evolocumab vs Standard Therapy

Evolocumab Cumulative Incidence of CV Events

Guidance for Use of PSCK9 Inhibitors*

CETP Inhibitors: HDL-C and LDL-C Effects and Current Status

Abbreviations

Abbreviations (cont)

Abbreviations (cont)