Challenges to Liver Transplantation and Strategies to Improve Outcomes Philipp Dutkowski, Michael Linecker, Michelle L. DeOliveira, Beat Müllhaupt, Pierre-Alain Clavien  Gastroenterology  Volume 148, Issue 2, Pages 307-323 (February 2015) DOI: 10.1053/j.gastro.2014.08.045 Copyright © 2015 AGA Institute Terms and Conditions

Figure 1 Five-year patient - and graft survival for the most common indications for LT as reported by the European Transplant registry (ELTR).2 Data for perihilar carcinoma (PHC) is obtained from 12 US centers.58 Gastroenterology 2015 148, 307-323DOI: (10.1053/j.gastro.2014.08.045) Copyright © 2015 AGA Institute Terms and Conditions

Figure 2 Mayo clinic treatment scheme and outcome of patients receiving neoadjuvant treatment followed by LT for PHC. Of the 247 patients with neoadjuvant treatment, 64% could proceed to LT resulting in a five-year survival of 69%. Figure courtesy Prof. C. Rosen. Gastroenterology 2015 148, 307-323DOI: (10.1053/j.gastro.2014.08.045) Copyright © 2015 AGA Institute Terms and Conditions

Figure 3 One year mortality after LT in relation to the balance of risk (BAR)-score.116 While post-transplant mortality remains below or equal 20% up to BAR score of 18, the risk to die after LT increases exponentially above BAR 18. Gastroenterology 2015 148, 307-323DOI: (10.1053/j.gastro.2014.08.045) Copyright © 2015 AGA Institute Terms and Conditions