Focus on lymphangiogenesis in tumor metastasis Marc G. Achen, Bradley K. McColl, Steven A. Stacker  Cancer Cell  Volume 7, Issue 2, Pages 121-127 (February 2005) DOI: 10.1016/j.ccr.2005.01.017 Copyright © 2005 Elsevier Inc. Terms and Conditions

Figure 1 Development of lymphatic vessels in embryogenesis and cancer Some of the proteins that are important in these events are shown underneath each section. Arrows denote the direction of lymph flow in the lymphatic vessels. A more extensive review of these processes with full lists of supporting references is presented elsewhere (Baldwin et al., 2002; Oliver, 2004). A recent report has called into question the involvement of LEC precursors in tumor lymphangiogenesis (He et al., 2004b). The role of FOXC2 has recently been delineated (Petrova et al., 2004). Cancer Cell 2005 7, 121-127DOI: (10.1016/j.ccr.2005.01.017) Copyright © 2005 Elsevier Inc. Terms and Conditions