The V410I (G1228A) variant of the caspase-10 gene is a common polymorphism in the Danish population by Kirsten Grønbæk, Tine Dalby, Jesper Zeuthen, Elisabeth Ralfkiaer, and Per Guldberg Blood Volume 95(6):2184-2185 March 15, 2000 ©2000 by American Society of Hematology
Detection of the V410I (G1228A) variant of the caspase-10 gene in DNA from healthy blood donors.(A) Representative denaturing gradient gel electrophoresis (DGGE) analysis of a region encompassing nucleotides 1186-1322 (codons 396-441) of the caspase-10 gene. Detection of the V410I (G1228A) variant of the caspase-10 gene in DNA from healthy blood donors.(A) Representative denaturing gradient gel electrophoresis (DGGE) analysis of a region encompassing nucleotides 1186-1322 (codons 396-441) of the caspase-10 gene. (B) Direct sequence analysis of a sample with aberrant DGGE pattern, showing the G1228A variant. Kirsten Grønbæk et al. Blood 2000;95:2184-2185 ©2000 by American Society of Hematology