Cost Effectiveness and Optimal Outcomes in HF

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Presentation transcript:

Cost Effectiveness and Optimal Outcomes in HF

Content Overview

The Importance of Considering Cost Effectiveness

Epidemiology and Costs Associated With HF Care

Costs Accumulated During Hospitalization Eclipse All Other HF-Related Costs

Measuring Cost Effectiveness

Measuring Cost Effectiveness (cont)

New Therapies for HF

SOC vs Treatment With New Agents

Pure Heart Rate Reduction Through If Current Inhibition

Ivabradine SHIFT Study

Effect of Ivabradine on Outcomes

Hypothetical Cost Projections in 1 Year: 1-Million-Member Insurance Plan

SHIFT: Ivabradine Improves QoL in Patients With HF

Role of Heart Rate as a CV Risk Biomarker

PARADIGM-HF (Sacubitril/Valsartan) Results

Sacubitril/Valsartan Decreases Risk of Recurrent Hospitalizations for Worsening HF

Cost Effectiveness of Sacubitril/Valsartan

Cost Effectiveness of Sacubitril/ Valsartan (cont)

Challenging Conventional Wisdom…

Angioedema AEs During Randomized Treatment

Concluding Remarks

Abbreviations

Abbreviations (cont)