Cost Effectiveness and Optimal Outcomes in HF
Content Overview
The Importance of Considering Cost Effectiveness
Epidemiology and Costs Associated With HF Care
Costs Accumulated During Hospitalization Eclipse All Other HF-Related Costs
Measuring Cost Effectiveness
Measuring Cost Effectiveness (cont)
New Therapies for HF
SOC vs Treatment With New Agents
Pure Heart Rate Reduction Through If Current Inhibition
Ivabradine SHIFT Study
Effect of Ivabradine on Outcomes
Hypothetical Cost Projections in 1 Year: 1-Million-Member Insurance Plan
SHIFT: Ivabradine Improves QoL in Patients With HF
Role of Heart Rate as a CV Risk Biomarker
PARADIGM-HF (Sacubitril/Valsartan) Results
Sacubitril/Valsartan Decreases Risk of Recurrent Hospitalizations for Worsening HF
Cost Effectiveness of Sacubitril/Valsartan
Cost Effectiveness of Sacubitril/ Valsartan (cont)
Challenging Conventional Wisdom…
Angioedema AEs During Randomized Treatment
Concluding Remarks
Abbreviations
Abbreviations (cont)