Genome-editing Technologies for Gene and Cell Therapy

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Genome-editing Technologies for Gene and Cell Therapy Morgan L Maeder, Charles A Gersbach  Molecular Therapy  Volume 24, Issue 3, Pages 430-446 (March 2016) DOI: 10.1038/mt.2016.10 Copyright © 2016 Official journal of the American Society of Gene & Cell Therapy Terms and Conditions

Figure 1 Mechanisms of double-strand break repair. Molecular Therapy 2016 24, 430-446DOI: (10.1038/mt.2016.10) Copyright © 2016 Official journal of the American Society of Gene & Cell Therapy Terms and Conditions

Figure 2 Common DNA targeting platforms for genome editing. Molecular Therapy 2016 24, 430-446DOI: (10.1038/mt.2016.10) Copyright © 2016 Official journal of the American Society of Gene & Cell Therapy Terms and Conditions

Figure 3 Ex vivo and in vivo strategies for therapeutic genome editing. Molecular Therapy 2016 24, 430-446DOI: (10.1038/mt.2016.10) Copyright © 2016 Official journal of the American Society of Gene & Cell Therapy Terms and Conditions

Figure 4 Diversity of targets for therapeutic genome editing. Molecular Therapy 2016 24, 430-446DOI: (10.1038/mt.2016.10) Copyright © 2016 Official journal of the American Society of Gene & Cell Therapy Terms and Conditions