Figure 2. Infliximab treatment effect

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Figure 2. Infliximab treatment effect Infliximab treatment effect (A) Median EDSS-NBS scores of 15 patients calculated from a total of 123 clinical assessments are shown. Period corresponding to the time between median preinfliximab NBS duration (29.1 months, range 5.0–180.7 months) and the median follow-up time after infliximab initiation (39.0 months, range 16.0–104.9 months) are marked. The median EDSS-NBS scores start and continue to increase during the median preinfliximab NBS period, but clearly stabilize after the switch to infliximab. (B) Preimmunosuppression, postimmunosuppression preinfliximab, and postinfliximab disability accumulation rates for individual patients are shown. A positive disability accumulation rate indicates worsening disability. A zero value in disability accumulation rate indicates complete cessation of disability accumulation. A negative disability accumulation rate indicates improvement from enrollment disability level. EDSS-NBS = Expanded Disability Status Scale modified for neuro-Behçet syndrome. Burcu Zeydan et al. Neurol Neuroimmunol Neuroinflamm 2016;3:e258 © 2016 American Academy of Neurology