Validation of next-generation sequencing for comprehensive chromosome screening of embryos Allen Kung, Santiago Munné, Brandon Bankowski, Alison Coates,

Slides:

Advertisements

Similar presentations

Development of guideline-based quality indicators for recurrent miscarriage E. van den Boogaard, M. Goddijn, N.J. Leschot, F. van der Veen, J.A.M. Kremer,

Advertisements

Array CGH analysis shows that aneuploidy is not related to the number of embryos generated Baris Ata, Brian Kaplan, Hal Danzer, Michael Glassner, Michael.

Programmes and prospects for ovotechnology

Validation of microarray comparative genomic hybridization for comprehensive chromosome analysis of embryos Cristina Gutiérrez-Mateo, Ph.D., Pere Colls,

The clinical utility of next-generation sequencing for identifying chromosome disease syndromes in human embryos Junmei Fan, Li Wang, Hui Wang, Minyue.

Optimal euploid embryo transfer strategy, fresh versus frozen, after preimplantation genetic screening with next generation sequencing: a randomized controlled.

Attitudes and policies regarding access to fertility care and assisted reproductive technologies in Israel Daniel Sperling, Yael Simon Reproductive.

Diet and endometriosis risk: A literature review

Blastocyst-stage versus cleavage-stage embryo transfer in women with high oestradiol concentrations: randomized controlled trial Eman A. Elgindy, Ahmed.

Anastasia A. Theodosiou, Martin H. Johnson

Delphine Haouzi, Hervé Dechaud, Said Assou, John De Vos, Samir Hamamah

Cross-validation and predictive value of near-infrared spectroscopy algorithms for day-5 blastocyst transfer Aisling Ahlström, Matts Wikland, Lena Rogberg,

E. Jauniaux, I. Ben-Ami, R. Maymon Reproductive BioMedicine Online

Development and validation of a next-generation sequencing–based protocol for 24- chromosome aneuploidy screening of embryos Francesco Fiorentino, Ph.D.,

Group culture of human zygotes is superior to individual culture in terms of blastulation, implantation and life birth T. Ebner, O. Shebl, M. Moser,

Investigation of sperm telomere length as a potential marker of paternal genome integrity and semen quality Federica Cariati, Souraya Jaroudi, Samer.

E. Jauniaux, I. Ben-Ami, R. Maymon Reproductive BioMedicine Online

MiR-483–5p and miR-486–5p are down-regulated in cumulus cells of metaphase II oocytes from women with polycystic ovary syndrome Lin Shi, Shan Liu, Wanqiu.

Willem Ombelet Reproductive BioMedicine Online

Reduction in exposure of human embryos outside the incubator enhances embryo quality and blastulation rate Jun Qiang Zhang, Xiu Ling Li, Yuzhu Peng,

L. L. van Loendersloot, M. van Wely, S. Repping, F. van der Veen, P. M

Freeze-all can be a superior therapy to another fresh cycle in patients with prior fresh blastocyst implantation failure Bruce S Shapiro, Said T Daneshmand,

Fresh transfer outcome predicts the success of a subsequent frozen transfer utilizing blastocysts of the same cohort L.F. Doherty, J.R. Martin, U. Kayisli,

Gillian M. Lockwood Reproductive BioMedicine Online

Establishment and validation of a score to predict ovarian response to stimulation in IVF Clelia Chalumeau, Jessika Moreau, Nicolas Gatimel, Clementine.

Why are reproductive cancers more common in nulliparous women?

Increased incidence of mosaicism detected by FISH in murine blastocyst cultured in vitro Tanya V. Sabhnani, Aisha Elaimi, Hanan Sultan, Adel Alduraihem,

Moniek van der Zanden, Annemiek W. Nap Reproductive BioMedicine Online

What’s on the mind of IVF consumers?

S Munné, E Fragouli, P Colls, MG Katz-Jaffe, WB Schoolcraft, D Wells

Non-invasive viability assessment of day-4 frozen–thawed human embryos using near infrared spectroscopy Carlijn G. Vergouw, Lucy L. Botros, Kevin Judge,

Piraye Yurttas Beim, Michael Elashoff, Tina T. Hu-Seliger

Working to eliminate multiple pregnancies: a success story in Québec

Sarah McCredie, William Ledger, Christos A. Venetis

Effect of N-acetyl-cysteine after ovarian drilling in clomiphene citrate-resistant PCOS women: a pilot study A. Nasr Reproductive BioMedicine Online

Does early morphology provide additional selection power to blastocyst selection for transfer? F. Guerif, M. Lemseffer, J. Leger, R. Bidault, V. Cadoret,

Cumulative live-birth delivery after IVF/ICSI since the progressive introduction of single- embryo transfer D. De Neubourg, C. Daels, M. Elseviers, K.

Individual demands of human embryos on IVF culture medium: influence on blastocyst development and pregnancy outcome B. Wirleitner, P. Vanderzwalmen,

Endometrial injury to overcome recurrent embryo implantation failure: a systematic review and meta-analysis Neelam Potdar, Tarek Gelbaya, Luciano G.

The origin and significance of additional aneuploidy events in couples undergoing preimplantation genetic diagnosis for translocations by array comparative.

Effect of energy expenditure and physical activity on the outcomes of assisted reproduction treatment Mert Kucuk, Fadime Doymaz, Bulent Urman Reproductive.

Association of skewed X chromosome inactivation and idiopathic recurrent spontaneous abortion: a systematic review and meta-analysis Yilun Sui, Qianqian.

Cross-border reproductive care: a review of the literature

Lisa Cummins, Juliette Koch, Suha Kilani

Effect of chromosomal polymorphisms of different genders on fertilization rate of fresh IVF–ICSI embryo transfer cycles Ji Liang, Yongsheng Zhang, Yang.

Construction and validation of a prediction model to minimize twin rates at preserved high live birth rates after IVF Katarina Kebbon Vaegter, Lars Berglund,

Stanley Paul Leibo (1937–2014): scientist, mentor and friend

A clinically useful simplified blastocyst grading system

Should we be promoting embryo transfer at blastocyst stage?

Stephen C. Collins, Esther Chan Reproductive BioMedicine Online

Pietro Gambadauro, Ramesan Navaratnarajah

Karyomapping identifies second polar body DNA persisting to the blastocyst stage: implications for embryo biopsy Christian S. Ottolini, Shaun Rogers,

Implication of apoptosis in sperm cryoinjury

Selection of embryos for transfer in IVF: ranking embryos based on their implantation potential using morphological scoring Laura van Loendersloot, Madelon.

Samuel Kofi Arhin, Yu Zhao, XiaoSheng Lu, Mandika Chetry, JieQiang Lu

The Alpha Consensus Meeting on the professional status of the clinical embryologist: proceedings of an expert meeting Reproductive BioMedicine Online

C Almeida, M Sousa, A Barros Reproductive BioMedicine Online

Effect of piroxicam administration before embryo transfer on IVF outcome: a randomized controlled trial Luca Dal Prato, Andrea Borini Reproductive BioMedicine.

Elective single-embryo transfer: persuasive communication strategies can affect choice in a young British population O.B.A. van den Akker, S. Purewal

Ovarian reserve screening before contraception?

Live birth following early follicular phase oocyte collection and vitrified-warmed embryo transfer 8 days later Safak Hatırnaz, Ebru Hatırnaz, Baris.

GT Volpato, DC Damasceno, WG Kempinas, MVC Rudge, IMP Calderon

I. Verginadis, I. P. Kosmas, Y. Simos, A. Velalopoulou, I

Implantation of fresh and thawed–warmed embryos in single embryo transfer cycles: interpreting the initial beta-HCG Cynthia K. Sites, Peter St Marie,

Programmes and prospects for ovotechnology

Limitations of a time-lapse blastocyst prediction model: a large multicentre outcome analysis Kirstine Kirkegaard, Alison Campbell, Inge Agerholm, Ursula.

Claudio Manna, Loris Nanni, Alessandra Lumini, Sebastiana Pappalardo

Randomized controlled trial of benzocaine versus placebo spray for pain relief at hysterosalpingogram E.A. Bachman, S. Senapati, M.D. Sammel, S.K. Kalra

China’s model of egg donation is a policy lesson for Britain

A. Finn, L. Scott, Thomas O’Leary, D. Davies, J. Hill

Presentation transcript:

Validation of next-generation sequencing for comprehensive chromosome screening of embryos Allen Kung, Santiago Munné, Brandon Bankowski, Alison Coates, Dagan Wells Reproductive BioMedicine Online Volume 31, Issue 6, Pages 760-769 (December 2015) DOI: 10.1016/j.rbmo.2015.09.002 Copyright © 2015 Reproductive Healthcare Ltd. Terms and Conditions

Figure 1 Comparison of a BlueGnome array-comparative genomic hybridization (aCGH) profile to next-generation sequencing (NGS)-produced Integrated Genome Viewer (IGV) profile. An example of a blastocyst sample processed using both aCGH and NGS (Illumina microarrays and the Ion Torrent PGM). The upper panel is the graphical visualization of the NGS analysis using IGV. The lower panel is the graphical representation of the array profile. Both samples presented are scored as an XY, monosomy 4, 11, and a partial monosomy on chromosome 13 from q21.32 to q34. Reproductive BioMedicine Online 2015 31, 760-769DOI: (10.1016/j.rbmo.2015.09.002) Copyright © 2015 Reproductive Healthcare Ltd. Terms and Conditions