Advisor: Paul Thompson

Slides:

Advertisements

Similar presentations

Introduction to Pneumatic Components Build a Working Pneumatic Circuit

Advertisements

Pneumatic Cylinders Chapter 3.

Systems Review 1 ATC Chapter 4.

Page 1 MDS Installation. Page 2 Contents  Introduction  Outdoor Unit Installation  Indoor Unit Installation  Refrigerant Pipe Work  Gas Charge 

Module 6 : Flow control valves

Neonatal Chest Compression Device Courtney Gallagher Jillian Zeber Advisor: Dr. Walsh, Vanderbilt NICU.

Ms 4.20 pneumatic cylinders/Tieh SF1 Pneumatic Cylinders.

Discrete Control Logic 1. Pneumatic circuits - Low forces - Discrete, fixed travel distances - Rotational or reciprocating motion Main components: compressor,

Team 10, Catheter Wash System Problem TERUMO® Medical Corporation, manufactures medical catheters for use in arteries and veins These catheters must be.

FIRST Pneumatics Team 1425 Wilsonville Robotics. Agenda Components Components Basic System Design Basic System Design Applications Applications Tricks.

4-1 Chapter 4 Overview b The DCM is very complex Mechanical, electrical, hydraulic and safety systems all work together Mechanical, electrical, hydraulic.

Drug Delivery & Tissue Engineering Laboratory

Some basics for FIRST Robotics

Presented by Jon Pannell

Pneumatic Shifting and Clutching and integration

Generating Motion Moving a part adds no value (except in packaging) Moving a tool adds no value unless work is done on part. So, we want to avoid moving.

Bangarang Musical Engineering University of Notre Dame Department of Aerospace and Mechanical Engineering Group Members: Roberto Ayala, Ryan Bradley, Pat.

Generating Motion Moving a part adds no value (except in packaging)‏ Moving a tool adds no value unless work is done on part. So, we want to avoid moving.

ME8843 The George W. Woodruff School of Mechanical Engineering ME 8843 Advanced Mechatronics Instructor: Professor Charles Ume Introduction to Hydraulic.

Team Members: Team Leader- Jeremy Glynn Communicator- Jeremy Schaefer BSAC- Mike Conrardy BWIG- Adam Goon Client- Ian Rowland, Ph.D., Department Of Radiology.

Pneumatic Actuators Brief Overview Kunal Sinha Grad General Engineering EFR : 2 per min.

Neonatal Chest Compression Device Courtney Gallagher Jillian Zeber Advisor: Dr. Walsh, Vanderbilt NICU.

Critical Current Probe Mid-Point Review Amy Eckerle Andrew Whittington Philip Witherspoon Team 16 NHMFL Applied Superconductivity Center 1.

Microelectronics Clean Room Electrical and Computer Engineering Orbital Tube Welder by Clayton Gatewood.

Electro-Pneumatics Module 1

Intra-Operative fluid warmer device. Department of Reconstructive Sciences, Health Campus, USM.

Mentors Workshop Pneumatic Sub-System Mark McLeod Team 358 Festo/Hauppauge H.S. F For I Inspiration and R Recognition of S Science and T Technology.

An Opening in the Abdomen An Opening in the Market: Hernia Tensiometer GROUP 2: Martha Ingram Megan Johnston Chelsea Samson.

Four- Stroke Small Engines

Manual Control Systems: Pneumatics “A Slice of Mechanical Engineering” Mr. J. Butler ● Department of Technology & Engineering ● John Jay High School ●

IV Tubing Organizer Blake Hondl, Amit Mehta, Ryan Pope, Kristen Sipsma, April Zehm, Katie Zenker BME 200/300 October 10, 2003.

Vacuum Fundamentals High-Vacuum Technology Course Week 6 Paul Nash HE Subject Leader (Engineering)

Problem Statement Project Proposal Design a device that will reduce the time of a medial malleolus fracture repair surgery Design a device that simplifies.

Authors Joel Rotroff Ben Moga Tom Pearce Hani Bou-Reslan BME 402 April 30th, 2004.

Lesson Using Pneumatic Systems. Interest Approach Can you explain how air makes a pneumatic hand tool work?

Warlocks 8/5/05 TMU Pneumatics on Robots u Simplified model Compressed Air Tank Geek Safety Glasses 60 lbs Pneumatic Cylinder Whoa! That’s a lot of force.

Generating Motion Moving a part adds no value (except in packaging) Moving a tool adds no value unless work is done on part. So, we want to avoid moving.

Generating Motion Moving a part adds no value (except in packaging) Moving a tool adds no value unless work is done on part. So, we want to avoid moving.

Probing The Of. Experience Pain Pain Team Members Jeff Swift Anna Karas Stacey Hoebel Advisor Prof. Willis Tompkins Client Dr. Christopher Coe UW-Madison.

An Inhalation System to Infect Laboratory Animals.

Dilution Refrigerators with Superconducting Magnets

Engineering Concepts Chapter 5 Terms. ACTUATOR A device that transfers fluid or electrical energy into mechanical energy.

Air Cylinders Convert the energy contained in the compressed air

Air condition installation

H & P Formulas Engineering II – August The parts and values of concern…. D 1 = diameter of cylinder (in) D 2 = diameter of piston rod (in) P 1 =

Discrete Control Logic

Elevator Controller for Individual with Multiple Sclerosis

Double Acting Cylinder

Engineering II – August 2016

ARAC/H/F Air-cooled water chillers, free-cooling chillers and heat pumps Range: kW.

Attachment 1-5: Fluid Power Circuit Examples

HYDRAULICS & PNEUMATICS

Opti-Purge® FAST INFLATION PURGE SYSTEM

Logic Functions Pneumatics Module 7.

Pixel CO2 Cooling Status

AUTOMATED LIQUID DELIVERY SYSTEM

Industrial Electronics

THERMAL PROPERTIES OF MATTER

INTRODUCTION TO PNEUMATICS

ET 438B Sequential Control and Data Acquisition

Erlenmeyer Flask An Erlenmeyer Flask is a cone-shaped container with neck, so you can hold the flask or attach a clamp or use a stopper. They are used.

Generating Motion Moving a part adds no value (except in packaging)

Generating Motion Moving a part adds no value (except in packaging)

Module – 4: Single Acting Cylinder

IENG 475: Computer-Controlled Manufacturing Systems

IR Beam Transport Status

Introduction to Electro-pneumatic

Presentation transcript:

Advisor: Paul Thompson TISSUE SAMPLE PREPARATION DEVICE FOR BIOCHEMICAL ANALYSIS Clients: Dr. Jeff Ross, Charles Tessier UW Medical School Department of Oncology Presented by: Sara Alford Christine Koranda Carla Maas Ryan Roth Advisor: Paul Thompson

PROJECT RATIONALE Biochemical analysis on tumor sample Automation in preparation process Potential clinical applications

PROBLEM STATEMENT To design a device that completes the preparation process done manually to prepare a tissue sample for biochemical analysis. Freeze tissue (with liquid nitrogen) Grind tissue to a powder

EXISTING TECHNOLOGY Jet Pulverizer© Bio-Pulverizer© BeadBeater© Accessed from www.jetpul.com Bio-Pulverizer© Accessed from www.biospec.com BeadBeater© Accessed from www.biospec.com

DESIGN REQUIREMENTS Freeze sample (<1 gram) Grind to powder similar to powdered sugar (~10 mm) Avoid sample loss

DESIGN CONSTRAINTS Materials must withstand cold temperatures (-196oC) Device should fit on a lab bench Components easy to clean

Pneumatic Impulse Sampler DESIGN SOLUTION Pneumatic Impulse Sampler Strengths Grinding pattern control Inexpensive Constant downward force Weakness Compressed air required

PROTOTYPE FEATURES Pneumatic cylinder Grinding head Electrical control Grinding chamber Insulating chamber

GRINDING CHAMBER AND HEAD Matching contours Minimal sample spray Stainless steel design 4” 1”

INSULATING CHAMBER Stainless steel Polystyrene Inner shell Provides support and connection Polystyrene Outer shell Provides insulation for grinding chamber 4” 2.75”

PNEUMATIC SYSTEM COMPONENTS air supply regulator solenoid valve pneumatic cylinder pivot mount

Improvement on flasher Astable mode → pulses ELECTRICAL CONTROL Improvement on flasher More control over time on/off Astable mode → pulses 555 timer circuit → logic relay Potentiometer to change values

R2, C – extend ON and OFF time Pot – extends only ON time

ELECTRICAL CONTROL

MISCELLANEOUS COMPONENTS Christmas light flasher Christmas lights Spiked fitting off regulator 1/4” tubing Ring clamps

OPERATIONAL PROTOTYPE Cylinder pounds 3-4 times/second Rod does not completely retract Ideal: avoids sample spillage Cylinder fitting and tubing protrude too far Interferes with alignment Need elbow joint

OPERATIONAL PROTOTYPE

PROTOTYPE TESTING Preliminary Test: grinding room temperature substance Secondary Test: integrate cooling meat or mouse liver with liquid nitrogen Final Testing: quantify grinding centrifuge and measure loose protein

FUTURE CONSIDERATIONS Space constraints Reduce excess base size to save lab space Minimize buckling Increase range of movement at current pivot joint Temperature alarm Informs technician to add more coolant Integrate twisting motion Shearing forces grind sample

QUESTIONS?