Selecting MM Therapy in Patients With Comorbidities

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Presentation transcript:

Selecting MM Therapy in Patients With Comorbidities

Agenda

Program Goals and Disclosure

Managing the Patient With Diabetes and MM

Diabetes and MM

Corticosteroids

Peripheral Neuropathy in Multiple Myeloma

Diabetic Autonomic Neuropathy

Managing Peripheral Neuropathy

Key Takeaways

MM Therapeutic Agents Associated AEs

Treating Patients With Renal Impairment

Renal Impairment in MM

Management

Dose Modifications With Renal Impairment

Key Takeaways

Treating Patients With a History of Thromboembolism

Risk of Thromboembolism in MM

VTE Incidence With Immunomodulatory Agents

Prophylaxis

Management

Treating Patients With a History of Cardiac Disease

Background

ASPIRE KRd vs Rd

ENDEAVOR Carfilzomib/Dex vs Bortezomib/Dex

Carfilzomib in Patients With Cardiac History

Other MM Agents and Cardiotoxicity

Balancing Efficacy and Convenience for the Frail Patient

MM Patients Are Heterogeneous

IMWG Geriatric Assessment

IMWG Frailty Score ADL and IADL Components

FIRST Trial Continuous Rd vs Rd-18 vs MPT

UPFRONT VD vs VTP vs VMP

Key Takeaways

Optimizing Adherence for Patients With Comorbidities

Components of Adherence

Patient and Caregiver Education

Impact of Comorbidities

Abbreviations

Abbreviations

Abbreviations