A Mitochondrial Stratigraphy for Island Southeast Asia

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A Mitochondrial Stratigraphy for Island Southeast Asia Catherine Hill, Pedro Soares, Maru Mormina, Vincent Macaulay, Dougie Clarke, Petya B. Blumbach, Matthieu Vizuete-Forster, Peter Forster, David Bulbeck, Stephen Oppenheimer, Martin Richards  The American Journal of Human Genetics  Volume 80, Issue 1, Pages 29-43 (January 2007) DOI: 10.1086/510412 Copyright © 2007 The American Society of Human Genetics Terms and Conditions

Figure 1 Map of Taiwan and Southeast Asia, showing both modern coastlines (darker shading) and the 120-m depth contour below sea level (lighter shading), indicating the extent of Sundaland at the Last Glacial Maximum. Sampling locations or populations are indicated by bold circles and are labeled with short codes if they were from a specific location or population. Taiwan: ATA = Atayal; BUN = Bunun; AMI = Ami; PAI = Paiwan. ISEA: MED = Medan; PAD = Padang; PEK = Pekanbaru; PLB = Palenbang; BGK = Bangka; KK = Kota Kinabalu; BAN = Banjarmasin; MND = Manado; PAL = Palu; TOR = Toraja; UJP = Ujung Padang; MTR = Mataram; WAI = Waingapu. Map outline kindly provided by H. Voris and C. Simpson, Field Museum of Natural History, Chicago.3 The American Journal of Human Genetics 2007 80, 29-43DOI: (10.1086/510412) Copyright © 2007 The American Society of Human Genetics Terms and Conditions

Figure 2 Schematic tree of East Eurasian mtDNA haplogroups, displaying the various branches of macrohaplogroup M (A) and macrohaplogroup N (B) and indicating diagnostic control-region positions and coding-region positions tested. We here rename R1270 as R22, since R12 was used in a previous study.71 F1a3 is here defined solely by 16311 because the two other control-region sites mentioned as diagnostic by Kong et al.66 do not appear in our data set. The American Journal of Human Genetics 2007 80, 29-43DOI: (10.1086/510412) Copyright © 2007 The American Society of Human Genetics Terms and Conditions

Figure 3 PC analysis of mtDNA haplogroup frequencies in Taiwan and ISEA (Taiwanese data include that of Trejaut et al.41). The American Journal of Human Genetics 2007 80, 29-43DOI: (10.1086/510412) Copyright © 2007 The American Society of Human Genetics Terms and Conditions

Figure 4 Reduced median network of HVS-I sequences of haplogroup E in the region 16050–16400. The circles represent mtDNA HVS-I sequence types, shaded according to region and with an area proportional to their frequency in each region. Links are labeled with the nucleotide position of mutations; letters following positions indicate transversions, and the others are transitions. Mutations that have occurred more than once in the tree are underlined. Coding-region positions that were sequenced are indicated in italics. Subclades are labeled, and the M9 ancestor is indicated (arrow). The American Journal of Human Genetics 2007 80, 29-43DOI: (10.1086/510412) Copyright © 2007 The American Society of Human Genetics Terms and Conditions

Figure 5 Spatial frequency distributions, created using the Kriging algorithm of the Surfer package, of haplogroups E (A), M7c1c (B), D5 (C), and Y2 (D). Samples from each island were merged to a central location, indicated with a point, to reduce any effect of error in small samples. The American Journal of Human Genetics 2007 80, 29-43DOI: (10.1086/510412) Copyright © 2007 The American Society of Human Genetics Terms and Conditions

Figure 6 Reduced median network of HVS-I sequences of haplogroup M7c1c. They are labeled as in figure 4. The M7c1 ancestor is indicated (arrow). The American Journal of Human Genetics 2007 80, 29-43DOI: (10.1086/510412) Copyright © 2007 The American Society of Human Genetics Terms and Conditions