Preventing Thrombosis During and Post-Hospitalization: New Paradigms in Clinical Care
Global Burden of VTE
Global Burden of VTE (cont)
Thrombosis UK
Virchow's Triad
Thrombosis in Medical Patients
Other Contributing Factors
Preventing Thrombosis During and Post-Hospitalization: New Paradigms in Clinical Care
Patients at Risk for VTE: Surgical Patients
Patients at Risk for VTE: Medical Patients
Patients at Risk for VTE: Other Factors
Preventing Thrombosis During and Post-Hospitalization: New Paradigms in Clinical Care
Patients at Risk for VTE
Multi-Disciplinary Approach
Electronic Alerts Reduce VTE
Thromboprophylaxis
Non-Pharmacologic Prophylaxis
Pharmacologic Prophylaxis
Summary
Summary (cont)
Preventing Thrombosis During and Post-Hospitalization: New Paradigms in Clinical Care
Trials of VTE Prophylaxis in Hospitalized Medical Patients
Previous Studies of Extended Thromboprophylaxis in Acute Medically Ill Patients
APEX Study Design
MAGELLAN D-Dimer
APEX Results
APEX Net Clinical Benefit (VTE or Major Bleed)
APEX Dose Reduction
Betrixaban FDA Approval
MARINER Trial Medical Patients at High Risk of VTE
MARINER vs APEX
Summary
Preventing Thrombosis During and Post-Hospitalization: New Paradigms in Clinical Care
VTE Risk After Discharge
VTE Risk Remains After Discharge
Improving Patient Outcomes
Abbreviations