by Thomas Rasmussen, Linda Jensen, Lone Honoré, and Hans Erik Johnsen

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Presentation transcript:

by Thomas Rasmussen, Linda Jensen, Lone Honoré, and Hans Erik Johnsen Frequency and kinetics of polyclonal and clonal B cells in the peripheral blood of patients being treated for multiple myeloma by Thomas Rasmussen, Linda Jensen, Lone Honoré, and Hans Erik Johnsen Blood Volume 96(13):4357-4359 December 15, 2000 ©2000 by American Society of Hematology

Thomas Rasmussen et al. Blood 2000;96:4357-4359 ©2000 by American Society of Hematology

Levels of CD19+ and clonal cells among PBMNCs Levels of CD19+ and clonal cells among PBMNCs.The level of CD19+ (▪) and clonal cells (⧫) among PBMNCs as determined by flow cytometry and real-time ASO IgH PCR. In patient MM-1, the level of CD19 mRNA (▴) was measured by quantitative real-time CD19 RT-PCR. Levels of CD19+ and clonal cells among PBMNCs.The level of CD19+ (▪) and clonal cells (⧫) among PBMNCs as determined by flow cytometry and real-time ASO IgH PCR. In patient MM-1, the level of CD19 mRNA (▴) was measured by quantitative real-time CD19 RT-PCR. The amount of CD19 mRNA is given as the fraction of β-actin mRNA. Serial PB samples were obtained at diagnosis, after 3 cycles of VAD, after cyclophosphamide (Cy), before (pre-Tx) and after PBSC transplantation. Thomas Rasmussen et al. Blood 2000;96:4357-4359 ©2000 by American Society of Hematology