Long-Term Survival of Patients With pN2 Lung Cancer According to the Pattern of Lymphatic Spread Antoine Legras, MD, Pierre Mordant, MD, PhD, Alex Arame,

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Long-Term Survival of Patients With pN2 Lung Cancer According to the Pattern of Lymphatic Spread Antoine Legras, MD, Pierre Mordant, MD, PhD, Alex Arame, MD, Christophe Foucault, MD, Antoine Dujon, MD, Françoise Le Pimpec Barthes, MD, PhD, Marc Riquet, MD, PhD The Annals of Thoracic Surgery Volume 97, Issue 4, Pages 1156-1162 (April 2014) DOI: 10.1016/j.athoracsur.2013.12.047 Copyright © 2014 The Society of Thoracic Surgeons Terms and Conditions

Fig 1 Schematic representation of the different patterns of lymphatic spread from the right lung: (A) pN0N2-1S; (B) pN1N2-1S; (C) pN0N2-2S; and (D) pN1N2-2S. The Annals of Thoracic Surgery 2014 97, 1156-1162DOI: (10.1016/j.athoracsur.2013.12.047) Copyright © 2014 The Society of Thoracic Surgeons Terms and Conditions

Fig 2 Long-term survival according to the cN status: cN0 (n = 238) median 30 months, 5-year 32%; cN1 (n = 96) median 19 months, 5-year 20.3%; cN2 (n = 537) median 21 months, 5-year 22.7% (p = 0.0015). The Annals of Thoracic Surgery 2014 97, 1156-1162DOI: (10.1016/j.athoracsur.2013.12.047) Copyright © 2014 The Society of Thoracic Surgeons Terms and Conditions

Fig 3 Long-term survival according to the pN status and the type of pN2 involvement. (A) Long-term survival of pN0, pN1, and pN2 patients. pN0 (n = 2,317) median 80 months, 5-year 58.6%, 10-year 37.3%. pN1 (n = 722) median 48 months, 5-year 45.1%, 10-year 26.8%. pN2 (n = 871) median 23 months, 5-year 25.4%, 10-year 17% (p < 0.001). (B) Long-term survival of pN2-1S and pN2-2S. pN2-1S (n = 575) median 26 months, 5-year 29.8%, 10-year 20.6%. pN2-2S (n = 296) median 16 months, 5-year 16.8%, 10-year 9.7% (p < 0.001). (C) Long-term survival of pN0N2-1S, pN0N2-2S, pN1N2-1S, pN1N2-2S patients (p < 0.001). The Annals of Thoracic Surgery 2014 97, 1156-1162DOI: (10.1016/j.athoracsur.2013.12.047) Copyright © 2014 The Society of Thoracic Surgeons Terms and Conditions