GO Annotation from different sources

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Presentation transcript:

GO Annotation from different sources

Secondary Sources of GO annotation EXAMPLES: public databases (eg. NCBI, UniProtKB) genome browsers (eg. Ensembl) array vendors (eg. Affymetrix) CONSIDERATIONS: What is the original source? When was it last updated? Are evidence codes displayed?

C. Obtaining GO annotations from Secondary Sources AIM: Look at how different public resources and tools display GO.

GO annotation obtained for chick GAPDH (P00356) from different sources: QuickGO (primary source) UniProtKB database NCBI Entrez Gene page Ensembl browser Affymetrix chick array g:profiler gene expression analysis tool

QuickGO

1.

2.

Comparison of Chicken GAPDH GO annotation obtained from different sources. GO evidence codes not reported.