Innovative Insulin Combinations: A New strategy for the Person With T2DM
Program Overview
Current Gaps in Insulin Therapy
The Role of Basal Insulin
Treatment Gaps Related to Titration
Patient-Led Titration of Insulin
Clinical Inertia
Intensification of Insulin
Premixed Insulins
Basal-Bolus Therapy
GLP-1 RA Mechanism of Action
Basal Insulin Plus GLP-1 RA—Free Combination
Basal Insulin/GLP-1 RA—Fixed-Ratio Combination
Formulations—Fixed-Ratio Basal Insulin/GLP-1 RA Combinations
DUAL V: Study Design
DUAL V: Key Results
DUAL V: Adverse Events
LixiLan-L Trial: Study Design
LixiLan-L Trial: Key Clinical Findings
LixiLan-L Trial: Key Clinical Findings (cont)
Potential Challenges With Fixed-Ratio Combinations
Fixed-Ratio Combination Basal Insulin/GLP-1 RA in Clinical Practice
Summary
Abbreviations