Pathway Tools Workshop © 2013 SRI International

SRI International An independent, nonprofit corporation Founded by Stanford University in 1946 Independent in 1970; changed name from Stanford Research Institute to SRI International in 1977 More than ~2,000 employees More than 20 locations worldwide Silicon Valley - Headquarters Washington, D.C. Princeton, New Jersey Harrisonburg, Virginia St. Petersburg, Florida State College, Pennsylvania Arecibo, Puerto Rico Tokyo, Japan OPPORTUNITIES PROFILE INNOVATIONS CAPABILITIES PROGRAMS

SRI Organization Information and Computing Sciences BioSciences Engineering Systems And Sciences Education Physical Sciences 27 November 201827 November 201827 November 2018

Technology Spin-off Ventures Growth opportunities that bring SRI innovations to market Publicly Traded Robotics Speech recognition for customer service Electroadhesion for materials handling Innovative robots for manufacturing/service Surgical robotics DNA testing services* Information Technology Video enhancement systems Virtual personal assistant for the iPhone* Customer service tools* Video-on-demand services** Educational gaming platform Travel search and planning Smart calendar for iPhone Wireless mesh networks* Next-generation personalized web search tool LCD technology* Stray voltage detection services Electronic signature solutions Real-time web video streaming and sharing Iris biometric identification* Panoramic image editing software* Technology for K-12 and higher education Digital imaging system Enterprise social media technology Materials Biomedical Metal “print and plate” manufacturing process Digital color printing applications* Super-bright LED light engines* Drug dispensing system* Drug discovery Electroactive polymers* (formerly Rosedale Medical) Glucose monitoring system Environmentally friendly light products* Disposable hearing aid* Portable power systems** Optical network components Anti-counterfeiting systems *Acquired or merged ** Dissolved OPPORTUNITIES PROFILE INNOVATIONS CAPABILITIES PROGRAMS

SRI Distinguished Innovations © 2013 SRI International

Computing SRI invented the foundations of personal computing Today: SRI spin-off Siri, acquired by Apple in 2010 and offered on the iPhone 4S, offers a virtual personal assistant—a new way to interact with the Internet on your mobile phone. Siri was born from the CALO project, an ambitious artificial intelligence program SRI led for DARPA. 1964–1968: SRI’s Doug Engelbart and team invented the computer mouse and demonstrated the foundations of personal computing. President Bill Clinton presents Doug Engelbart with the 2000 National Medal of Technology OPPORTUNITIES PROFILE INNOVATIONS CAPABILITIES PROGRAMS

Internet and Networks SRI was there “before the beginning” .com .gov .org 1969: SRI received the first logon to the ARPANET, predecessor of the Internet. 1970–1992: SRI ran the Network Information Center (NIC), the domain name registration clearinghouse for all computer hosts connecting to the ARPANET and Internet. SRI assigned all .com, .org, and .gov domain names. 1987: SRI’s pioneering network intrusion detection technology protects against malicious attacks. Today: For the Department of Homeland Security, SRI administers the Cyber Security R&D Center, which develops technology for protection of the U.S. cyber infrastructure through partnerships with industry, the venture community, and the research community. Today: SRI’s online Malware Threat Center helps network administrators understand current and emerging computer security threats and provides key network defense information.  OPPORTUNITIES PROFILE INNOVATIONS CAPABILITIES PROGRAMS

Workshop Goals Share exciting science in genomics and metabolic pathway bioinformatics New developments in Pathway Tools and BioCyc New science from user community Brainstorm about how to improve Pathway Tools and BioCyc Stimulate new collaborations

Administrative Details Please wear badges at all times; return at end of day SRI escort required to remainder of SRI’s campus Meals Restrooms Tuesday: Park in E-building parking lot Meet in A-building lobby for escort to I-building