Development and internal validation of a clinical rule to improve antibiotic use in children presenting to primary care with acute respiratory tract infection.

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Presentation transcript:

Development and internal validation of a clinical rule to improve antibiotic use in children presenting to primary care with acute respiratory tract infection and cough: a prognostic cohort study Prof Alastair D Hay, FRCGP, Niamh M Redmond, PhD, Sophie Turnbull, MSc, Hannah Christensen, PhD, Hannah Thornton, PhD, Prof Paul Little, FMedSci, Prof Matthew Thompson, PhD, Prof Brendan Delaney, MD, Andrew M Lovering, PhD, Peter Muir, PhD, John P Leeming, PhD, Barry Vipond, PhD, Beth Stuart, PhD, Prof Tim J Peters, FMedSci, Peter S Blair, PhD The Lancet Respiratory Medicine Volume 4, Issue 11, Pages 902-910 (November 2016) DOI: 10.1016/S2213-2600(16)30223-5 Copyright © 2016 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY-NC-ND license Terms and Conditions

Figure 1 Flow chart *Other reasons include perceived difficulties with completing symptom diary, language barriers, another child was already recruited, person attending with the child was not their carer, concerns about access to medical records, and child had complex needs. The Lancet Respiratory Medicine 2016 4, 902-910DOI: (10.1016/S2213-2600(16)30223-5) Copyright © 2016 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY-NC-ND license Terms and Conditions

Figure 2 Final model receiver operator characteristic curves for (A) coefficient and (B) points-based models The Lancet Respiratory Medicine 2016 4, 902-910DOI: (10.1016/S2213-2600(16)30223-5) Copyright © 2016 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY-NC-ND license Terms and Conditions