Preoperative Prophylactic Intraaortic Balloon Pump Reduces the Incidence of Postoperative Acute Kidney Injury and Short-Term Death of High-Risk Patients.

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Preoperative Prophylactic Intraaortic Balloon Pump Reduces the Incidence of Postoperative Acute Kidney Injury and Short-Term Death of High-Risk Patients Undergoing Coronary Artery Bypass Grafting: A Meta-Analysis of 17 Studies Jiayang Wang, MD, Wenyuan Yu, MD, Mingxin Gao, MD, Chengxiong Gu, MD, Yang Yu, MD, PhD The Annals of Thoracic Surgery Volume 101, Issue 5, Pages 2007-2019 (May 2016) DOI: 10.1016/j.athoracsur.2015.10.078 Copyright © 2016 The Society of Thoracic Surgeons Terms and Conditions

Fig 1 Flow chart of study selection process. (CABG = coronary artery bypass grafting.) The Annals of Thoracic Surgery 2016 101, 2007-2019DOI: (10.1016/j.athoracsur.2015.10.078) Copyright © 2016 The Society of Thoracic Surgeons Terms and Conditions

Fig 2 Meta-analysis of postoperative renal outcomes of high-risk patients undergoing coronary artery bypass grafting (CABG). (A) Effects of preoperative prophylactic intraaortic balloon pump (IABP) on the incidence of postoperative acute kidney injury (AKI) in high-risk patients undergoing CABG. (B) Subgroup analysis of the effects of preoperative prophylactic IABP on the incidence of postoperative AKI in high-risk patients undergoing off-pump CABG (OPCABG). (C) Effects of preoperative prophylactic IABP on postoperative renal replacement therapy in high-risk patients undergoing CABG. The solid squares indicate the mean difference and are proportional to the weights used in the meta-analysis. The solid vertical line indicates no effect. The dashed vertical line indicates the summary measure, with the associated diamond indicating the weighted mean difference and the lateral tips of the diamond indicating the associated 95% confidence intervals (CIs). The horizontal lines represent the 95% CI. (OR = odds risk.) The Annals of Thoracic Surgery 2016 101, 2007-2019DOI: (10.1016/j.athoracsur.2015.10.078) Copyright © 2016 The Society of Thoracic Surgeons Terms and Conditions

Fig 2 Meta-analysis of postoperative renal outcomes of high-risk patients undergoing coronary artery bypass grafting (CABG). (A) Effects of preoperative prophylactic intraaortic balloon pump (IABP) on the incidence of postoperative acute kidney injury (AKI) in high-risk patients undergoing CABG. (B) Subgroup analysis of the effects of preoperative prophylactic IABP on the incidence of postoperative AKI in high-risk patients undergoing off-pump CABG (OPCABG). (C) Effects of preoperative prophylactic IABP on postoperative renal replacement therapy in high-risk patients undergoing CABG. The solid squares indicate the mean difference and are proportional to the weights used in the meta-analysis. The solid vertical line indicates no effect. The dashed vertical line indicates the summary measure, with the associated diamond indicating the weighted mean difference and the lateral tips of the diamond indicating the associated 95% confidence intervals (CIs). The horizontal lines represent the 95% CI. (OR = odds risk.) The Annals of Thoracic Surgery 2016 101, 2007-2019DOI: (10.1016/j.athoracsur.2015.10.078) Copyright © 2016 The Society of Thoracic Surgeons Terms and Conditions

Fig 3 Meta-analysis on short-term death of high-risk patients undergoing coronary artery bypass grafting (CABG). (A) Effects of preoperative prophylactic intraaortic balloon pump (IABP) on short-term death in high-risk patients undergoing CABG. (B) Subgroup analysis of the effects of preoperative prophylactic IABP on short-term death in high-risk patients undergoing off-pump CABG. The solid squares indicate the mean difference and are proportional to the weights used in the meta-analysis. The solid vertical line indicates no effect. The dashed vertical line indicates the summary measure, with the associated diamond indicating the weighted mean difference and the lateral tips of the diamond indicating the associated 95% confidence intervals (CIs). (OB = observational study; OR = odds risk; RCT = randomized controlled trials.) The Annals of Thoracic Surgery 2016 101, 2007-2019DOI: (10.1016/j.athoracsur.2015.10.078) Copyright © 2016 The Society of Thoracic Surgeons Terms and Conditions