Synaptotagmins: That’s Why So Many

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Synaptotagmins: That’s Why So Many Chong Chen, Peter Jonas Neuron Volume 94, Issue 4, Pages 694-696 (May 2017) DOI: 10.1016/j.neuron.2017.05.011 Copyright © 2017 Terms and Conditions

Figure 1 Three Proposed Functions of Syt7 in Exocytosis and Endocytosis at Central Synapses (1) Asynchronous release during high-frequency stimulation (Luo and Südhof, 2017). (2) Synaptic facilitation of transmitter release (Jackman et al., 2016). (3) Rapid replenishment of the pool of synaptic vesicles (Liu et al., 2014). Syt 1 or 2 is drawn in red; Syt7 is represented in cyan. Whereas Syt1 or 2 are primarily located on synaptic vesicles, Syt7 is abundant on the plasma membrane (Li et al., 2017). Neuron 2017 94, 694-696DOI: (10.1016/j.neuron.2017.05.011) Copyright © 2017 Terms and Conditions