A Modern Magnetic Implant for Gastroesophageal Reflux Disease

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Presentation transcript:

A Modern Magnetic Implant for Gastroesophageal Reflux Disease Robert A. Ganz  Clinical Gastroenterology and Hepatology  Volume 15, Issue 9, Pages 1326-1337 (September 2017) DOI: 10.1016/j.cgh.2016.12.019 Copyright © 2017 AGA Institute Terms and Conditions

Figure 1 Magnetic attraction in the form of an expansible ring is ideally suited to the dynamic area of the GEJ. The properties of magnets provide a precise and permanent force to augment the LES. Unlike the use of springs or tissue to reinforce the antireflux barrier, magnetic force decreases with esophageal displacement. Clinical Gastroenterology and Hepatology 2017 15, 1326-1337DOI: (10.1016/j.cgh.2016.12.019) Copyright © 2017 AGA Institute Terms and Conditions

Figure 2 The magnetic sphincter is available in a range of sizes. The magnetic device is prevented from migrating (until fibrous encapsulation occurs) by surgically anchoring the device between the posterior vagus and the esophagus. Clinical Gastroenterology and Hepatology 2017 15, 1326-1337DOI: (10.1016/j.cgh.2016.12.019) Copyright © 2017 AGA Institute Terms and Conditions

Figure 3 The magnetic sphincter prevents inappropriate reflux, but opens to allow normal esophageal function, such as swallowing, belching, and vomiting. Not all of the magnetic beads separate with each swallow. Clinical Gastroenterology and Hepatology 2017 15, 1326-1337DOI: (10.1016/j.cgh.2016.12.019) Copyright © 2017 AGA Institute Terms and Conditions

Figure 4 The magnetic sphincter has consistently provided improvement across key clinical outcomes from multiple studies for (A) GERD-HRQOL, (B) PPI discontinuation, (C) reduction in esophageal acid exposure, and (D) elimination of moderate/severe regurgitation. MSA, magnetic sphincter augmentation. Clinical Gastroenterology and Hepatology 2017 15, 1326-1337DOI: (10.1016/j.cgh.2016.12.019) Copyright © 2017 AGA Institute Terms and Conditions

Figure 5 (A) Postoperative GERD-HRQL scores were comparable between magnetic augmentation (MA) and laparoscopic Nissen fundoplication (LF) and ranged from 0–5.0 after MA, compared with 3.5–5.1 after LF. (B) Discontinuation of PPIs was comparable between the treatments ranging from 76%–100% after MA and 63%–96.1% after LF. Clinical Gastroenterology and Hepatology 2017 15, 1326-1337DOI: (10.1016/j.cgh.2016.12.019) Copyright © 2017 AGA Institute Terms and Conditions

Figure 6 The magnetic sphincter augments the reflux barrier by expansible magnetic force, not bulk and rigidity as with the Angelchik prosthesis. The volume of the Angelchik was approximately 50 mL versus 1.2 mL for the magnetic sphincter. Clinical Gastroenterology and Hepatology 2017 15, 1326-1337DOI: (10.1016/j.cgh.2016.12.019) Copyright © 2017 AGA Institute Terms and Conditions