Volume 64, Issue 6, Pages (December 2003)

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Volume 64, Issue 6, Pages 2214-2221 (December 2003) Magnetic resonance measurements of renal blood flow as a marker of disease severity in autosomal-dominant polycystic kidney disease1  Bernard F. King, Vicente E. Torres, Marijn E. Brummer, Arlene B. Chapman, Kyongtae T. Bae, James F. Glockner, Kraisthith Arya, Joel P. Felmlee, Jared J. Grantham, Lisa M. Guay-Woodford, William M. Bennett, Saulo Klahr, Gladys H. Hirschman, Paul L. Kimmel, Paul A. Thompson, J. Phillip Miller, the Consortium for Radiologic Imaging Studies of Polycystic Kidney Disease (CRISP)  Kidney International  Volume 64, Issue 6, Pages 2214-2221 (December 2003) DOI: 10.1046/j.1523-1755.2003.00326.x Copyright © 2003 International Society of Nephrology Terms and Conditions

Figure 1 Magnetic resonance (MR) angiogram of the renal arteries in a patient with autosomal-dominant polycystic kidney disease (ADPKD). (A) Following the MR angiogram a flow acquisition MR pulse sequence (see Methods section for detailed description) is performed perpendicular to the renal artery. (B) The flow acquisition pulse sequence yields a set of cross-sectional images through the renal arteries and veins. Flow analysis is performed on the MR signal information contained within the renal artery. Kidney International 2003 64, 2214-2221DOI: (10.1046/j.1523-1755.2003.00326.x) Copyright © 2003 International Society of Nephrology Terms and Conditions

Figure 2 Analyses of patient with autosomal-dominant polycystic kidney disease (ADPKD). (A) Velocity, cross-sectional area, and blood flow plotted during 20 phases of the cardiac cycle in the left renal artery in a magnetic resonance (MR) flow acquisition of an ADPKD patient. (B) Cross-sectional flow acquisition images in the left renal artery of the same patient. Kidney International 2003 64, 2214-2221DOI: (10.1046/j.1523-1755.2003.00326.x) Copyright © 2003 International Society of Nephrology Terms and Conditions

Figure 3 Blood flow measurements repeated three times in 19 autosomal-dominant polycystic kidney disease (ADPKD) patients by radiologists A and B. The intrareviewer coefficients of variation were 1.2% and 1.4%. The average interreviewer coefficient of variation was 2.5%. Kidney International 2003 64, 2214-2221DOI: (10.1046/j.1523-1755.2003.00326.x) Copyright © 2003 International Society of Nephrology Terms and Conditions