Conservative versus surgical treatment of venous leg ulcers: A prospective, randomized, multicenter trial Wijnand B. van Gent, MD, Wim C. Hop, PhD, Marinus.

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Conservative versus surgical treatment of venous leg ulcers: A prospective, randomized, multicenter trial Wijnand B. van Gent, MD, Wim C. Hop, PhD, Marinus C. van Praag, MD, Albert J. Mackaay, MD, Edith M. de Boer, MD, Cees H. Wittens, MD Journal of Vascular Surgery Volume 44, Issue 3, Pages 563-571 (September 2006) DOI: 10.1016/j.jvs.2006.04.053 Copyright © 2006 The Society for Vascular Surgery Terms and Conditions

Fig 1 Trial profile. SEPS, Subfascial endoscopic perforating vein surgery. Journal of Vascular Surgery 2006 44, 563-571DOI: (10.1016/j.jvs.2006.04.053) Copyright © 2006 The Society for Vascular Surgery Terms and Conditions

Fig 2 Ulcer-free period per patient per 3 months in patients with an ulcer present before randomization for shorter or longer than 4 months (P < .001; analysis of variance). Journal of Vascular Surgery 2006 44, 563-571DOI: (10.1016/j.jvs.2006.04.053) Copyright © 2006 The Society for Vascular Surgery Terms and Conditions

Fig 3 The ulcer-free period per patient per 3 months in the surgical and conservative groups (analysis of variance, P = .14) Numbers along the horizontal axis represent legs still in follow-up at the particular time points for the two groups. Journal of Vascular Surgery 2006 44, 563-571DOI: (10.1016/j.jvs.2006.04.053) Copyright © 2006 The Society for Vascular Surgery Terms and Conditions

Fig 4 Ulcer-free period per patient per 3 months in first-time and recurrent ulceration patients (P < .001; analysis of variance). Error bars represent standard errors of the mean. Journal of Vascular Surgery 2006 44, 563-571DOI: (10.1016/j.jvs.2006.04.053) Copyright © 2006 The Society for Vascular Surgery Terms and Conditions

Fig 5 Ulcer-free period per patient per 3 months in patients treated in one of the centers (SFG; P = .02; analysis of variance). Journal of Vascular Surgery 2006 44, 563-571DOI: (10.1016/j.jvs.2006.04.053) Copyright © 2006 The Society for Vascular Surgery Terms and Conditions

Fig 6 Ulcer-free period per patient per 3 months in patients with a first-time ulcer and/or a medial ulcer in the surgical and conservative groups (P = .045; analysis of variance). Journal of Vascular Surgery 2006 44, 563-571DOI: (10.1016/j.jvs.2006.04.053) Copyright © 2006 The Society for Vascular Surgery Terms and Conditions

Fig 7 Cumulative healing rates according to randomized treatment groups (P = .24). Tickmarks note the ends of follow-up of patients. Journal of Vascular Surgery 2006 44, 563-571DOI: (10.1016/j.jvs.2006.04.053) Copyright © 2006 The Society for Vascular Surgery Terms and Conditions

Fig 8 Cumulative recurrence rates according to randomized treatment groups (not significant). Tickmarks note the ends of follow-up of patients. Journal of Vascular Surgery 2006 44, 563-571DOI: (10.1016/j.jvs.2006.04.053) Copyright © 2006 The Society for Vascular Surgery Terms and Conditions