Figure 2 Copy-number variations in multiple myeloma Figure 2 | Copy-number variations in multiple myeloma. a | Data provided are the average frequencies of recurrent chromosomal gain and loss reported in two studies in which single-nucleotide polymorphism (SNP) arrays were used to analyse samples from 114 (Ref. 55) and 192 (Ref. 76) patients with multiple myeloma. b | Frequency of focal changes in multiple myeloma. Data were obtained from a study using the GISTIC algorithm89 to analyse samples from 153 patients6. CNVs, copy-number variations. Manier, S. et al. (2016) Genomic complexity of multiple myeloma and its clinical implications Nat. Rev. Clin. Oncol. doi:10.1038/nrclinonc.2016.122