Volume 82, Issue 1, Pages 7-8 (July 2012)

Slides:

Advertisements

Similar presentations

Copyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings Dee Unglaub Silverthorn, Ph.D. H UMAN P HYSIOLOGY PowerPoint ® Lecture Slide.

Advertisements

Plasma sodium and hypertension

Renal manifestations in Fabry disease and therapeutic options

Giovanni Davogustto, MD, Thomas J. Wang, MD, Deepak K. Gupta, MD

Viper venom for diabetic nephropathy

Volume 83, Issue 3, Pages (March 2013)

Volume 12, Issue 5, Pages (November 2010)

Volume 71, Issue 11, Pages (June 2007)

Volume 79, Issue 9, Pages (May 2011)

Hypertension in end-stage renal disease

The Case ∣ Acute renal failure and anemia

Viper venom for diabetic nephropathy

Volume 72, Issue 1, Pages (July 2007)

Long term regulation of Blood Pressure Nervous mechanisms are not capable of maintaining long term homeostasis Nervous system resets to new state----Receptor.

Pharmacology of cyclooxygenase-2 inhibition in the kidney

Volume 77, Issue 1, Pages 6-8 (January 2010)

Renoprotective effects of vitamin D analogs

Volume 58, Issue 1, Pages (July 2000)

Is there a pharmacologic basis for combination renin axis blockade?

Volume 71, Issue 5, Pages (March 2007)

Volume 84, Issue 2, Pages (August 2013)

Volume 74, Pages S55-S59 (December 2008)

Methotrexate in the urine

Biff F. Palmer, MD American Journal of Kidney Diseases

Comorbidity and confounding in end-stage renal disease

Volume 74, Issue 3, Pages (August 2008)

Volume 86, Issue 2, Pages (August 2014)

Volume 71, Issue 6, Pages (March 2007)

Vitamin D receptor: A highly versatile nuclear receptor

Volume 78, Issue 8, Pages (October 2010)

David M. Charytan, John P. Forman Kidney International

A physician's perseverance uncovers problems in a key nephrology study

Volume 69, Issue 12, Pages (June 2006)

Volume 69, Issue 3, Pages (February 2006)

Urinary biomarkers: the future looks promising

Volume 74, Issue 8, Pages (October 2008)

Volume 87, Issue 3, Pages (March 2015)

Volume 87, Issue 1, Pages (January 2015)

Atrial fibrillation in end-stage renal disease: an emerging problem

Volume 59, Issue 5, Pages (May 2001)

Nephrology Crossword: Glomerulonephritis

Volume 77, Issue 4, Pages (February 2010)

S. Susan Hedayati, Essam F. Elsayed, Robert F. Reilly

Volume 76, Issue 1, Pages 6-7 (July 2009)

Volume 73, Issue 9, Pages (May 2008)

The pathophysiology of edema formation in the nephrotic syndrome

Volume 71, Issue 11, Pages (June 2007)

Volume 82, Issue 9, Pages (November 2012)

Volume 81, Issue 1, Pages 7-9 (January 2012)

Does equal care give equal outcomes?

Molecular mechanisms of renal hypertrophy: Role of p27Kip1

Volume 72, Issue 2, Pages (July 2007)

Pablo A. Ureña Torres, Marc De Broe Kidney International

Toshinori Aoyagi, Taka-aki Koshimizu, Akito Tanoue

Volume 80, Issue 10, Pages (November 2011)

Volume 83, Issue 4, Pages (April 2013)

Is it the low-protein diet or simply the salt restriction?

Volume 65, Issue 4, Pages (April 2004)

Volume 71, Issue 9, Pages (May 2007)

Does an apple a day put hypertension in play?

Arya M. Sharma, Joachim Beige, Armin Distler Kidney International

Salt and water: a brief natural history

Aldosterone and potassium secretion by the cortical collecting duct

Volume 74, Issue 11, Pages (December 2008)

Volume 74, Issue 10, Pages (November 2008)

Volume 75, Issue 8, Pages (April 2009)

Integrative Physiology II: Fluid and Electrolyte Balance

Volume 59, Issue 5, Pages (May 2001)

Ronen Levi, Justin Silver Kidney International

Model of regulatory pathways for the mineralocorticoid receptor (MR) in intercalated cells: hyperkalemia and volume depletion. Model of regulatory pathways.

Presentation transcript:

Volume 82, Issue 1, Pages 7-8 (July 2012) Corin: a key protein of an adaptive renal mechanism to respond to salt variation? Richard Bouley Kidney International Volume 82, Issue 1, Pages 7-8 (July 2012) DOI: 10.1038/ki.2012.123 Copyright © 2012 International Society of Nephrology Terms and Conditions

Figure 1 Proposed role of corin in water and salt homeostasis. In high-salt-diet conditions, corin cleaves pro-atrial natriuretic peptide (Pro-ANP) into an active form (ANP) in the heart. To reduce sodium reabsorption, ANP inhibits the secretion of aldosterone from the adrenal gland and reduces secretion of renin from the kidney and subsequently the production of angiotensin II (Ang II). ANP will also reduce the activity of the epithelial sodium channel in kidney principal cells. Kidney International 2012 82, 7-8DOI: (10.1038/ki.2012.123) Copyright © 2012 International Society of Nephrology Terms and Conditions