Predictive value of Escherichia coli susceptibility in strains causing asymptomatic bacteriuria for women with recurrent symptomatic urinary tract infections.

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Predictive value of Escherichia coli susceptibility in strains causing asymptomatic bacteriuria for women with recurrent symptomatic urinary tract infections receiving prophylaxis M.A.J. Beerepoot, C.D.J. den Heijer, J. Penders, J.M. Prins, E.E. Stobberingh, S.E. Geerlings Clinical Microbiology and Infection Volume 18, Issue 4, Pages E84-E90 (April 2012) DOI: 10.1111/j.1469-0691.2012.03773.x Copyright © 2012 European Society of Clinical Infectious Diseases Terms and Conditions

FIG. 1 Flow diagram showing the pulsed-field gel-electrophoresis (PFGE) and antimicrobial susceptibility selection procedure for premenopausal women (a) and postmenopausal women (b). TMP/SMX, trimethoprim/sulfamethoxazole. Clinical Microbiology and Infection 2012 18, E84-E90DOI: (10.1111/j.1469-0691.2012.03773.x) Copyright © 2012 European Society of Clinical Infectious Diseases Terms and Conditions

FIG. 2 Kaplan–Meier curves for the cumulative probability of being urinary tract infection (UTI) -free during the 15 months of follow-up, for women with and without asymptomatic bacteriuria at baseline. No difference was observed between the two groups (p >0.05). Clinical Microbiology and Infection 2012 18, E84-E90DOI: (10.1111/j.1469-0691.2012.03773.x) Copyright © 2012 European Society of Clinical Infectious Diseases Terms and Conditions

FIG. 3 Example of pulsed-field gel-electrophoresis (PFGE) patterns. The patterns of 18 Escherichia coli strains, obtained from eight patients, are shown. Isolates belonging to one patient are indicated by horizontal lines above the PFGE lanes. For each patient, the first lane represents the asymptomatic strain, whereas the second (and third) lane(s) represent(s) the symptomatic strain(s). Two E. coli pairs had different PFGE patterns (patients 2 and 4). In patients 2 and 8, PFGE was performed on two symptomatic E. coli strains (lanes 4 and 5, and lanes 17 and 18, respectively) with different colony morphology on the blood agar plate, but a similar PFGE pattern. Clinical Microbiology and Infection 2012 18, E84-E90DOI: (10.1111/j.1469-0691.2012.03773.x) Copyright © 2012 European Society of Clinical Infectious Diseases Terms and Conditions