Food Chemicals Toxicity

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Presentation transcript:

Food Chemicals Toxicity On-line course Training program on Food Chemical Risk Assessment for developing country food safety regulators and the food Industry Chapter 2 (a-c) Food Chemicals Toxicity

Chapter 2.1 (a-c): Food chemicals – their toxicity OBJECTIVES Understanding the steps taking place from the intake of food chemicals their absorption, distribution in the body, metabolism and excretion (ADME) the observed toxic effects How to assess the severity of effects in animals and humans.

Chapter Content overall Absorption, distribution, metabolism and excretion of food chemiclas Toxicokinetics (how quick do processes happen) and toxicodynamics (effects) definition Examples of chemicals and toxicity targets and endpoints Threshold vs non-threshold mode of action Dose-response observations in more detail – animal based assays for data aquisition

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