Dead-space or dead-end: Can prolonged mechanical ventilation be predicted in all children after unifocalization? Tyson A. Fricke, MBBS, BMedSci, Igor.

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Presentation transcript:

Dead-space or dead-end: Can prolonged mechanical ventilation be predicted in all children after unifocalization? Tyson A. Fricke, MBBS, BMedSci, Igor E. Konstantinov, MD, PhD, FRACS The Journal of Thoracic and Cardiovascular Surgery Volume 156, Issue 3, Pages 1188-1189 (September 2018) DOI: 10.1016/j.jtcvs.2018.05.033 Copyright © 2018 Terms and Conditions

Figure 1 Enghoff's modification of Bohr's formula replaced alveolar partial CO2 pressure (PACO2) by arterial partial CO2 pressure (PaCO2) to calculate ratio between dead-space volume (Vd) and tidal volume (Vt). Although this formula is appropriate for patients who underwent unifocalization with complete repair, it might yield the wrong dead-space ventilation fraction (Vd/Vt) in those who underwent unifocalization without complete repair and were left with the right-to-left intracardiac shunt. Vd/Vt might predict prolonged ventilation after unifocalization in pulmonary atresia, although this might not be applicable to patients with right-to-left shunting. RV, Right ventricle; PA, pulmonary artery; VSD, ventricular septal defect. The Journal of Thoracic and Cardiovascular Surgery 2018 156, 1188-1189DOI: (10.1016/j.jtcvs.2018.05.033) Copyright © 2018 Terms and Conditions

Bohr's formula might miscalculate dead-space ventilation fraction in patients with right-to-left shunting. The Journal of Thoracic and Cardiovascular Surgery 2018 156, 1188-1189DOI: (10.1016/j.jtcvs.2018.05.033) Copyright © 2018 Terms and Conditions