Blood… The River of Life A delivery system of 6 quarts of liquid fun!!!

I. Functions of Blood Transports Oxygen to body cells Transports Carbon Dioxide and Waste from the body cells Transports food to body cells Contains disease fighters Regulates body temperature Transports hormones

II. Anatomy of Blood Plasma Liquid Part of Blood (92% Water) Contains salts, proteins, nutrients, waste, hormones, sugar, enzymes Non living

II. Anatomy of Blood B. Red Blood Cells Live 100-120 days No nucleus Contain Hemoglobin which carries oxygen Flattened Discs Made in bone marow

II. Anatomy of Blood White Blood Cells 1. Less than 1% of Blood 2. Complete cells (contain nucleus and organelles) 3. Protective army of cells used in Defense against foreign invaders 4. Can leave the circulatory system and go to damaged tissues

Anatomy of Blood The Five Types of White Blood Cells a. Neutrophils – Fight acute infection b. Eosinophils – Allergies and Parasites

(Cont) c. Basophils – Seen in inflammation d. Lymphocytes – Immune Response – make antibodies, fights tumors e. Monocytes – Fight chronic infections like TB

II. Anatomy of Blood Platelets 1. Fragments of Cells 2. Aid in Blood Clotting 3. Form a temporary plug to seal break in skin

Blood Types Inherited from parents Caused by carbohydrate markers on Red Blood Cells called Antigens Each blood type has a different Antigen

Blood Types Type A = A antigens Type B = B antigens Type AB = A and B antigens Type O = no antigens Rh + = + antigens Rh - = no antigens

If a cell doesn’t recognize the marker, it will produce proteins called antibodies that fight against it

Type A = makes anti-B antibodies Type B = makes anti- A antibodies Type AB = makes no antibodies Type O = makes Anti A and Anti B antibodies Rh + = no antibodies Rh - = anti RH+ antibodies

The Scoop on Blood Types Antigens ABO Rh A – A antigens B- B antigens AB – A & B antigens O – no antigens Rh+= antigen Rh - = no antigen Carbohydrates MARKERS ON CELL Used in ID

The Scoop on Blood Type Antibodies Rh ABO Bind to Antigens Anti-A Anti-B Anti Rh+ Proteins Find Invaders In plasma

Inheritance of Blood Types Type A = IAIA or IAi Type B = IBIB or Ibi Type AB = IAIB Type O = ii

Genetics of Blood Type i i IA IAi IAi IB IBi IBi Cross Type AB with Type O i i IA IAi IAi IB IBi IBi

Cross Type A heterozygous with Type B heterozygous