Cell Adhesion: Sizing Up a Sticky Situation Deborah Leckband Current Biology Volume 23, Issue 22, Pages R1008-R1011 (November 2013) DOI: 10.1016/j.cub.2013.10.018 Copyright © 2013 Elsevier Ltd Terms and Conditions
Figure 1 Cadherin clustering at intercellular junctions. Three possible mechanisms could control cadherin cluster (red) size, including precise size control (A), protein–protein interactions promote lateral clustering on the membrane (B), or kinetic balancing between cluster fusion and cluster fission (C). Each of these scenarios would predict a distribution of the concentration of clusters with n cadherins, cn versus the number of cadherins per cluster, as indicated below each of the illustrated hypothetical cluster patterns. Current Biology 2013 23, R1008-R1011DOI: (10.1016/j.cub.2013.10.018) Copyright © 2013 Elsevier Ltd Terms and Conditions