Magnitude and Kinetics of Decrease in Liver Stiffness After Antiviral Therapy in Patients With Chronic Hepatitis C: A Systematic Review and Meta-analysis  Siddharth Singh, Antonio Facciorusso, Rohit Loomba, Yngve T. Falck-Ytter  Clinical Gastroenterology and Hepatology  Volume 16, Issue 1, Pages 27-38.e4 (January 2018) DOI: 10.1016/j.cgh.2017.04.038 Copyright © 2018 AGA Institute Terms and Conditions

Figure 1 Study selection flowsheet. VCTE, vibration-controlled transient elastography. Clinical Gastroenterology and Hepatology 2018 16, 27-38.e4DOI: (10.1016/j.cgh.2017.04.038) Copyright © 2018 AGA Institute Terms and Conditions

Figure 2 Forest plot with individual studies showing magnitude and kinetics of decline in liver stiffness in patients with HCV who achieve sustained virologic response, as compared with baseline, before antiviral therapy. Clinical Gastroenterology and Hepatology 2018 16, 27-38.e4DOI: (10.1016/j.cgh.2017.04.038) Copyright © 2018 AGA Institute Terms and Conditions

Figure 3 Comparison of change in liver stiffness over time, in patients with HCV who achieve SVR versus patients who do not achieve SVR. Clinical Gastroenterology and Hepatology 2018 16, 27-38.e4DOI: (10.1016/j.cgh.2017.04.038) Copyright © 2018 AGA Institute Terms and Conditions

Supplementary Figure 1 Metaregression showing magnitude of change in liver stiffness by (A) baseline ALT, (B) proportion of patients with cirrhosis, and (C) baseline body mass index. Clinical Gastroenterology and Hepatology 2018 16, 27-38.e4DOI: (10.1016/j.cgh.2017.04.038) Copyright © 2018 AGA Institute Terms and Conditions

Supplementary Figure 2 Difference in liver stiffness at different time points in patients who achieve SVR versus those who do not achieve SVR, demonstrating net decline in liver stiffness. Clinical Gastroenterology and Hepatology 2018 16, 27-38.e4DOI: (10.1016/j.cgh.2017.04.038) Copyright © 2018 AGA Institute Terms and Conditions