Volume 8, Issue 4, Pages (August 2002)

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Volume 8, Issue 4, Pages 249-253 (August 2002) Regional vulnerability to chronic hypoxia and chronic hypoperfusion in the rat brain  Chikako Kawaguchi, Shunya Takizawa, Kiyoshi Niwa, Tokuzen Iwamoto, Ichiro Kuwahira, Hirotaka Kato, Yukito Shinohara  Pathophysiology  Volume 8, Issue 4, Pages 249-253 (August 2002) DOI: 10.1016/S0928-4680(02)00014-7

Fig. 1 The normal appearing cell count per 0.6 mm2 in cerebral frontal cortex. Sharp shows significant cell decline compare with control (#P<0.05). There is not a significant difference of normal appearing cell count between chronic hypoxia and chronic hypoperfusion. Pathophysiology 2002 8, 249-253DOI: (10.1016/S0928-4680(02)00014-7)

Fig. 2 The normal appearing cell count in hippocampus. Asterisk showed significant decline of normal appearing cell count compare to chronic hypoxia. (*P<0.05 compare with chronic hypoxia, one-way ANOVA followed by Fisher's PLSD). Pathophysiology 2002 8, 249-253DOI: (10.1016/S0928-4680(02)00014-7)

Fig. 3 A–C HE staining of frontal cortex. (A) Control. (B) Chronic hypoxia. (C) Chronic hypoperfusion. Pathy neuronal loss was observed. Pathophysiology 2002 8, 249-253DOI: (10.1016/S0928-4680(02)00014-7)

Fig. 4 A–C HE staining of CA3 in hippocampus. (A) Control. (B) Chronic hypoxia. (C) Chronic hypoperfusion. Dark neurons observed in chronic hypoxia and hypoperfusion, which is more severe in hypoperfusion. Pathophysiology 2002 8, 249-253DOI: (10.1016/S0928-4680(02)00014-7)