Measurement of endometrial tissue blood flow: a novel way to assess uterine receptivity for implantation Masao Jinno, M.D., Tsuneo Ozaki, M.D., Mitsutoshi.

Slides:

Advertisements

Similar presentations

Glycodelin is present in pinopodes of receptive-phase human endometrium and is associated with down-regulation of progesterone receptor B Anneli Stavreus-Evers,

Advertisements

Selective cyclo-oxygenase-2 inhibition induces regression of autologous endometrial grafts by down-regulation of vascular endothelial growth factor-mediated.

Sachiko Matsuzaki, M. D. , Takashi Murakami, M. D. , Shigeki Uehara, M

Expression of vascular endothelial growth factor-A and its receptor-1 in a luteal endometrium in patients with repeated in vitro fertilization failure

P27 and its ubiquitin ligase Skp2 expression in endometrium of IVF patients with repeated hormonal stimulation Shirly Lahav-Baratz, Mara Koifman, Edmond.

Matthias W. Laschke, M. D. , Antje Elitzsch, D. V. M

Relationship between apoptosis and the number of macrophages in eutopic endometrium from women with and without endometriosis Donald P Braun, Ph.D.,

Expression of cyclooxygenase-2 and vascular endothelial growth factor in ovarian endometriotic cysts and their relationship with angiogenesis Seyit Temel.

The disturbance of TH17-Treg cell balance in adenomyosis

Patrizia Carrarelli, Ph. D. , Chih-Fen Yen, M. D. , Felice Arcuri, Ph

Mesenchymal stem cells derived from Wharton jelly of the human umbilical cord ameliorate damage to human endometrial stromal cells Xiaoqing Yang, M.S.,

Glycodelin A is expressed differentially in normal human endometrial tissue throughout the menstrual cycle as assessed by immunohistochemistry and in.

Hypoxia inducible factor and microvessels in peri-implantation endometrium of women with recurrent miscarriage Xiaoyan Chen, M.Phil., Lingming Jiang,

Michelle Nisolle, M. D. , Ph. D. , Françoise Casanas-Roux, B. S

Xinmei Zhang, M. D. , Bangchun Lu, M. D. , Xiufeng Huang, M. D

Expression of motility-related molecule Cdc42 in endometrial tissue in women with adenomyosis and ovarian endometriomata Gaia Goteri, M.D., Andrea Ciavattini,

Placental polyp with prominent neovascularization

Expression of microtubule associated protein 2 and synaptophysin in endometrium: high levels in deep infiltrating endometriosis lesions Martina Gori,

Differential expression of vascular endothelial growth factor angiogenic factors in different endometrial compartments in women who have an elevated progesterone.

Khaleque Newaz Khan, M. D. , Ph. D. , Michio Kitajima, M. D

Min Li, M. Sc. , Dong Liu, M. Sc. , Li Wang, Ph. D. , Weizhou Wang, B

Increased expression of p21-activated kinase in adenomyosis

Laura D. Almquist, M. D. , Creighton E. Likes, M. D

Endometrial expression and in vitro modulation of the iron transporter divalent metal transporter-1: implications for endometriosis Carlos Patricio Alvarado-Díaz,

Metalloproteinases, vascular endothelial growth factor, and angiopoietin 1 and 2 in eutopic and ectopic endometrium Costantino Di Carlo, M.D., Marika.

Alessandro Fasciani, M. D. , Guido Bocci, M. D. , Jing Xu, M. D. , Ph

Temporal expression pattern of progesterone receptor in the uterine luminal epithelium suggests its requirement during early events of implantation Honglu.

A tissue-engineered human endometrial stroma that responds to cues for secretory differentiation, decidualization, and menstruation Stacey C. Schutte,

Action of mifepristone on the expression of insulin-like growth factor binding protein-1 mRNA and protein during the early luteal phase in the human oviduct

Vascular density and distribution of vascular endothelial growth factor (VEGF) and its receptor VEGFR-2 (Flk-1) are significantly higher in patients with.

Aquaporin 7 expression in postimplantation mouse uteri: a potential role for glycerol transport in uterine decidualization Hongying Peng, M.D., Ying.

Dioxin may promote inflammation-related development of endometriosis

Development and characterization of an endometrial tissue culture model for study of early implantation events Tian-Min Ye, M.D., Ph.D., Ronald T.K.

Matthias W. Laschke, M. D. , Antje Elitzsch, D. V. M

Submucosal uterine leiomyomas have a global effect on molecular determinants of endometrial receptivity Beth W. Rackow, M.D., Hugh S. Taylor, M.D. Fertility.

Pathophysiologic features of “thin” endometrium

Effect of aromatase inhibitors on ectopic endometrial growth and peritoneal environment in a mouse model of endometriosis Mariela Bilotas, Ph.D., Gabriela.

Xiao-Yu Pan, Ph. D. , Xue Li, M. D. , Zhan-Ping Weng, Ph. D

Effect of mifepristone on the expression of endometrial secretory leukocyte protease inhibitor in new medroxyprogesterone acetate users Aimin Li, M.D.,

Possible roles of oxytocin receptor and vasopressin-1α receptor in the pathomechanism of dysperistalsis and dysmenorrhea in patients with adenomyosis.

Discovery of biomarkers of endometrial receptivity through a minimally invasive approach: a validation study with implications for assisted reproduction

Endometrial growth and uterine blood flow: a pilot study for improving endometrial thickness in the patients with a thin endometrium Akihisa Takasaki,

HOXA-10 and E-cadherin expression in the endometrium of women with recurrent implantation failure and recurrent miscarriage Yihua Yang, Ph.D., Xiaoyan.

Immunohistochemical detection of heparanase-1 expression in eutopic and ectopic endometrium from women with endometriosis Xiulong Xu, Ph.D., Jianchi.

Up-regulation of endocrine gland-derived vascular endothelial growth factor but not vascular endothelial growth factor in human ectopic endometriotic.

Effect of pentoxifylline on vascular endothelial growth factor C and flk-1 expression on endometrial implants in the rat endometriosis model Nikos F.

Status of nucleolar channel systems in uterine secretions accurately reflects their prevalence—a marker for the window of implantation—in simultaneously.

Rahi Victory, M. D. , F. R. C. S. C. , Ghassan M. Saed, Ph. D

Vascular endothelial growth factor polymorphisms (−460C/T, +405G/C, and 936C/T) and endometriosis: their influence on vascular endothelial growth factor expression

Min Li, M. Sc. , Dong Liu, M. Sc. , Li Wang, Ph. D. , Weizhou Wang, B

Murat Ulukus, M. D. , E. Cagnur Ulukus, M. D. , Ege N

Ching-wen Cheng, Ph. D. , Stephen K. Smith, M. D. , D

Putative stem cell activity of human endometrial epithelial and stromal cells during the menstrual cycle Kjiana Elkje Schwab, B.Biomed.Sci. (Hons.),

Pasquale Florio, M. D. , Ph. D. , Paulo B. Torres, M. D

Macrophage migration inhibitory factor expression in the intrauterine endometrium of women with endometriosis varies with disease stage, infertility status,

Philip Kressin, M. D. , Eva-Maria Wolber, Ph. D. , Harald Wodrich, Ph

Lois A. Salamonsen, Ph. D. , Tracey Edgell, Ph. D. , Luk J. F

Ying-Fang Zhou, M. D. , Takao Mori, Ph. D. , Hideki Kudo, M. D

Concentration of vascular endothelial growth factor released by cultured human luteinized granulosa cells is higher in women with polycystic ovaries than.

Alterations in expression of endometrial endothelial nitric oxide synthase and αvβ3 integrin in women with endometriosis Omid Khorram, M.D., Ph.D., Bruce.

Effects of mifepristone on expression of endothelial nitric oxide synthase in human endometrium during the implantation phase Xiaoxi Sun, M.D., Xiaoyan.

Microvascular density, vascular endothelial growth factor A, and its receptors in endometrial blood vessels in patients with menorrhagia Miriam Mints,

Prediction of chromosome misalignment among in vitro matured human oocytes by spindle imaging with the PolScope Wei-Hua Wang, Ph.D., David L Keefe, M.D.

Effect of ovarian steroids on gene expression profile in human uterine microvascular endothelial cells Tadahiro Yasuo, M.D., Kotaro Kitaya, M.D. Fertility.

Expression of vascular endothelial growth factor and thrombospondin-1 mRNA in patients with endometriosis Xian-Jie Tan, Ph.D., Jing-He Lang, M.D., Dong-Yuan.

Absence of endometrium as a cause of primary amenorrhea

Direct injection of vascular endothelial growth factor into the ovary of mice promotes follicular development Ramiro Quintana, M.D., Laura Kopcow, M.D.,

Increased endometrial thickness on the day of human chorionic gonadotropin injection does not adversely affect pregnancy or implantation rates following.

Quantification of nucleolar channel systems: uniform presence throughout the upper endometrial cavity Michael J. Szmyga, M.S., Eli A. Rybak, M.D., M.P.H.,

Middle to lower uterine segment embryo transfer improves implantation and pregnancy rates compared with fundal embryo transfer David Frankfurter, M.D.,

Presentation transcript:

Measurement of endometrial tissue blood flow: a novel way to assess uterine receptivity for implantation Masao Jinno, M.D., Tsuneo Ozaki, M.D., Mitsutoshi Iwashita, M.D., Yukio Nakamura, M.D., Akihiko Kudo, Ph.D., Hiroshi Hirano, M.D., Ph.D. Fertility and Sterility Volume 76, Issue 6, Pages 1168-1174 (December 2001) DOI: 10.1016/S0015-0282(01)02897-7

FIGURE 1 Hysterofiberscope equipped with a laser blood-flowmeter. The endometrium is illuminated by linearly polarized laser light through the optical fiber probe; scattered light is detected simultaneously by the probe. Jinno. Endometrial blood flow and receptivity. Fertil Steril 2001. Fertility and Sterility 2001 76, 1168-1174DOI: (10.1016/S0015-0282(01)02897-7)

FIGURE 2 Immunohistochemical localization of vascular endothelial growth factor (VEGF) in human secretory endometrium. VEGF immunoreactivity, shown as red areas, is confined to glandular epithelial cells, with little detectable immunofluorescence in stromal cells. Immunoreactivity is stronger in (A) a woman who became pregnant than (B) one who did not. Nuclei are shown in green. Scale bar = 10μm. Jinno. Endometrial blood flow and receptivity. Fertil Steril 2001. Fertility and Sterility 2001 76, 1168-1174DOI: (10.1016/S0015-0282(01)02897-7)

FIGURE 3 Time-averaged mean of endometrial tissue blow flow (mETBF) in the fundus (F) and anterior (A), posterior (P), right-lateral (R), and left-lateral (L) walls of the endometrium in normal and abnormal uteri. ∗ = P<.0001 vs. A/P/R/L group (ANOVA and Fisher’s PLSD). Jinno. Endometrial blood flow and receptivity. Fertil Steril 2001. Fertility and Sterility 2001 76, 1168-1174DOI: (10.1016/S0015-0282(01)02897-7)