Empirical Research on Psychopathy Biological Influences THE PSYCHOPATH Empirical Research on Psychopathy Biological Influences J.B. Helfgott, PhD/ Department of Criminal Justice/ Seattle University

Biological Origins of Psychopathy Research gaining the most attention in recent years is in neuroanatomy and neuropsychology with focus on the: Prefrontal cortex Orbitofrontal cortex Limbic System Amygdala J.B. Helfgott, PhD/ Department of Criminal Justice/ Seattle University

J.B. Helfgott, PhD/ Department of Criminal Justice/ Seattle University The Human Brain J.B. Helfgott, PhD/ Department of Criminal Justice/ Seattle University

Components of the Human Brain J.B. Helfgott, PhD/ Department of Criminal Justice/ Seattle University

J.B. Helfgott, PhD/ Department of Criminal Justice/ Seattle University Brain Imaging Positron Emission Tomography (PET) first scanning method to provide information on brain function as well as anatomy used in conjunction with small amounts of radiolabeled compounds to visualize brain anatomy and function. Magnetic Resonance Imaging (MRI) newest most versatile medical imaging technology available - useful for imaging the brain and spine Produces highly refined images of the body's interior without surgery by using strong magnets and pulses of radio waves J.B. Helfgott, PhD/ Department of Criminal Justice/ Seattle University

Research by Adrian Raine Found that violent offenders have shrunken prefrontal cortexes Affective but not predatory murderers show anomalies on PET scans J.B. Helfgott, PhD/ Department of Criminal Justice/ Seattle University

J.B. Helfgott, PhD/ Department of Criminal Justice/ Seattle University The Prefrontal Cortex Plays a role in higher cognitive functions, such as concentration, planning, judgment, emotions, and personality determination. Damage to the orbitofrontal cortex may play a role in violent behavior. J.B. Helfgott, PhD/ Department of Criminal Justice/ Seattle University

Research by James Blair Dysfunction in the psychopath’s brain lies in the amygdala Amygdala regulates FEAR and emotion -dysfunction of Amygdala explains the psychopath’s lack of fear and empathy. J.B. Helfgott, PhD/ Department of Criminal Justice/ Seattle University

J.B. Helfgott, PhD/ Department of Criminal Justice/ Seattle University The Amygdala Part of the Limbic System located within the temporal lobe controls social and sexual behavior and other emotions. plays a critical role in processing emotion and mediating fear. J.B. Helfgott, PhD/ Department of Criminal Justice/ Seattle University

J.B. Helfgott, PhD/ Department of Criminal Justice/ Seattle University Additional Findings Murderers: Reduced prefrontal activity Poor functioning of the left angular gyrus (lies at junction of the temporal, parietal, and occipital regions) – linked to reduced verbal ability Reductions in functioning of the corpus callosum (which provides lines of communication between left and right hemispheres) – associated with inappropriate emotional expression and inability to comprehend long-term implications. Psychopaths: Inhibited startle reflex in response to emotionally aversive stimuli. Low autonomic arousal as measured through skin conductivity/galvanic skin response J.B. Helfgott, PhD/ Department of Criminal Justice/ Seattle University

J.B. Helfgott, PhD/ Department of Criminal Justice/ Seattle University The Final Word? Theories are not mutually exclusive Must be considered within an integrative framework Evidence from neuroimaging studies, and biological research findings in general, is promising but inconclusive. J.B. Helfgott, PhD/ Department of Criminal Justice/ Seattle University

J.B. Helfgott, PhD/ Department of Criminal Justice/ Seattle University Treatment Treatment implications of the biological perspective?                                                           J.B. Helfgott, PhD/ Department of Criminal Justice/ Seattle University

J.B. Helfgott, PhD/ Department of Criminal Justice/ Seattle University Recommended Reading Raine, A. (1993). The Psychopathology of Crime. New York: Academic Press. Raine, A. & Dunkin, J. (1990). The genetic and psychophysiological basis of antisocial behaviour: Implications for counseling and therapy. Journal of Counseling & Development, 68, 637-644. Raine, A. & Sanmartin, J. (Eds.) (2001). Violence and Psychopathy. New York: Kluwer Academic/Plenum Publishers. J.B. Helfgott, PhD/ Department of Criminal Justice/ Seattle University