OPKO’s Emerging Markets OPKO Chile – Pharma Genexx, S.A. Acquired October 2009 Also acquired ALD Distribution, Ltd. in April 2012 Rapidly growing sales from > 100 products Revenues: 2010: $18.0 MM 2011: $21.5 MM Expected 2012: $26-$30 MM OPKO Mexico – Pharmacos Exakta S.A. de C.V. Acquired February 2010 25 products across a range of therapeutic indications Primarily branded ophthalmics Expanding proprietary focus 2010: $3.8 MM 2011: $6.4 MM OPKO FineTech – FineTech Pharmaceuticals, Ltd. Acquired December 2011 Develops and produces high value, high potency APIs (active pharmaceutical ingredients) FDA registered, state-of-the-art facility in Nesher, Israel Revenue: 1Q 2012: $1.6 MM