Personalized and rapid test for food-related allergy

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Presentation transcript:

Personalized and rapid test for food-related allergy Mikaël Frossard, MSc, Natalia Gasilova, PhD, Lionel Arlettaz, MD, PhD, Eric Dayer, MD, Hubert H. Girault, PhD Journal of Allergy and Clinical Immunology Volume 141, Issue 6, Pages 2297-2300 (June 2018) DOI: 10.1016/j.jaci.2017.11.065 Copyright © 2018 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Fig 1 Developed allergy CRD procedure (A). MALDI-MS spectra obtained during the milk allergy CRD of the commercial blood serum using solution of BSA (B), LF (C), β-LG (D), whey (E) fraction of whole UHT milk, casein fraction of whole UHT milk (F), whey fraction of skimmed milk powder (G), and casein fraction of skimmed milk powder (H). MBs, Magnetic beads. Journal of Allergy and Clinical Immunology 2018 141, 2297-2300DOI: (10.1016/j.jaci.2017.11.065) Copyright © 2018 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Fig 2 MALDI-MS spectra obtained during the milk allergy CRD of the clinical blood serum using allergenic whey fraction (A and B). The diagnosis was confirmed by PMF (C and D) and by using pure solution of LF (E) and BSA (F). MALDI-MS spectra corresponding to the cross-reactivity tests using the whey fractions of sheep (G) and goat (H) milk. Journal of Allergy and Clinical Immunology 2018 141, 2297-2300DOI: (10.1016/j.jaci.2017.11.065) Copyright © 2018 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Fig E1 Journal of Allergy and Clinical Immunology 2018 141, 2297-2300DOI: (10.1016/j.jaci.2017.11.065) Copyright © 2018 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Fig E2 Journal of Allergy and Clinical Immunology 2018 141, 2297-2300DOI: (10.1016/j.jaci.2017.11.065) Copyright © 2018 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Fig E3 Journal of Allergy and Clinical Immunology 2018 141, 2297-2300DOI: (10.1016/j.jaci.2017.11.065) Copyright © 2018 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Fig E4 Journal of Allergy and Clinical Immunology 2018 141, 2297-2300DOI: (10.1016/j.jaci.2017.11.065) Copyright © 2018 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Fig E5 Journal of Allergy and Clinical Immunology 2018 141, 2297-2300DOI: (10.1016/j.jaci.2017.11.065) Copyright © 2018 American Academy of Allergy, Asthma & Immunology Terms and Conditions