Pulmonary artery remodeling in transposition of the great arteries: relevance for neoaortic root dilatation Shirin Lalezari, MD, Mark G Hazekamp, MD,

Slides:

Advertisements

Similar presentations

Max B. Mitchell, MD The Journal of Thoracic and Cardiovascular Surgery

Advertisements

Manuel J. Antunes, MD, PhD, DSc

Wound healing around and within saphenous vein bypass grafts

Translocation of a single coronary artery from the nonfacing sinus in the arterial switch operation: Long-term patency of the interposition graft Igor.

Surgery for congenital diseases of the aorta

Mitral stenosis with pulmonary hypertension: We should operate early

Reconstruction of pulmonary artery with porcine small intestinal submucosa in a lamb surgical model: Viability and growth potential Lorenzo Boni, MD,

Congenital thoracoabdominal aortic aneurysm

Jacques A. M. van Son, MD, PhD, William D. Edwards, MD, Gordon K

Dissection of a dilated autograft root

Valve-sparing aortic root replacement in a patient with a rare connective tissue disorder: Arterial tortuosity syndrome Tomaso Bottio, MD, PhD, Gianluigi.

Aortic root translocation with atrial switch: Another surgical option for congenitally corrected transposition of the great arteries with isolated pulmonary.

Coding of coronary arterial origin and branching in congenital heart disease: The modified Leiden Convention Adriana C. Gittenberger-de Groot, PhD, Wilke.

Ascending aorta dilation in association with bicuspid aortic valve: A maturation defect of the aortic wall Nimrat Grewal, MD, Adriana C. Gittenberger-de.

Ross procedure in the setting of anomalous aortic origin of a coronary artery Amit Pawale, MD, Bobby Yanagawa, MD, PhD, Robin Varghese, MD, Paul Stelzer,

New ascending aortic aneurysm model in rats reproduces main structural features of degenerative ascending thoracic aortic aneurysms in human beings Narcis.

Valve-sparing procedure and Lecompte maneuver in patients with late aortic regurgitation and aortic aneurysm after the arterial switch operation Yih-Sharng.

Are preoperative B-type natriuretic peptide levels associated with outcome after pulmonary artery banding and the double switch operation in patients.

John S. Ikonomidis, MD, PhD, FRCS(C), Abe DeAnda, MD, D

Form ever follows function

Acute angulation of the aortic arch predisposes a patient to ascending aortic dilatation and aortic regurgitation late after the arterial switch operation.

William M. DeCampli, MD, PhD

Vascular matrix remodeling in patients with bicuspid aortic valve malformations: implications for aortic dilatation Paul W.M Fedak, MD, Mauro P.L de.

Multilevel data analysis: What? Why? How?

Coronary transfer during arterial switch—the heart of the matter?

The pathology of fresh and cryopreserved homograft heart valves: An analysis of forty explanted homograft valves David R. Koolbergen, MD, Mark G. Hazekamp,

Paul H. Schoof, MDa, Adriana C

Histologic abnormalities of the ascending aorta and pulmonary trunk in patients with bicuspid aortic valve disease: Clinical relevance to the ross procedure

Timing of surgery for pulmonary embolism: An evolving paradigm

Risk-corrected impact of mechanical versus bioprosthetic valves on long-term mortality after aortic valve replacement Ole Lund, MD, PhD, Martin Bland,

Valve-sparing root repair: V-shaped remodeling can be performed in all sinuses Paul P. Urbanski, MD, PhD The Journal of Thoracic and Cardiovascular Surgery

Direct visualization of the aortic cusp from the left ventricle during aortic root reimplantation Yutaka Okita, PhD, MD, Takanori Oka, MD, Shunsuke Miyahara,

Three-dimensional evaluation of ductal tissue in coarctation of the aorta using X-ray phase-contrast tomography Ryuma Iwaki, MD, Hironori Matsuhisa,

Sinus node structural changes in patients with long-standing chronic atrial fibrillation Aquilino Hurlé, MD, PhD, Vicente Climent, MD, PhD, Damian Sánchez-Quintana,

Anomalous left coronary artery from the pulmonary artery with an intramural course within the aortic wall: Report of 3 surgical cases Steven P. Goldberg,

Phillip S. Naimo, MD, Edward Buratto, MBBS, Igor E

Analysis of the aortic root in patients with tetralogy of Fallot undergoing early repair: Form follows function Katrien François, MD, PhD, David Creytens,

Surgical strategies for anomalous origin of the left coronary artery from the right pulmonary artery with an intramural aortic course: A report of 10.

Support Your Specialty

Pathologic features of cryopreserved aortic allograft implanted in the active infection Akitoshi Yamada, MD, Kenji Okada, MD, Rei Takahashi, MD, Yutaka.

The morphologic nature of noncommitted ventricular septal defects in specimens with double-outlet right ventricle Rudolf P. Beekman, MD, PhDa, Margot.

Variation in Coronary Anatomy in Adult Patients Late After Arterial Switch Operation: A Computed Tomography Coronary Angiography Study Caroline E. Veltman,

The aortic valve–sparing operation

Jennifer Engle, MD, Hazim J. Safi, MD, Omid Abbassi, MD, Dimitrios C

Aortic root and valve surgery after arterial switch operation

Prashanth Vallabhajosyula, MD, MS, Caroline Komlo, BS, Tyler J

Surgery for aortic and mitral valve disease in the United States: A trend of change in surgical practice between 1998 and 2005 Scott D. Barnett, PhD,

Igor E. Konstantinov, MD, PhD, Peter Pohlner, MB, BS, FRACS

Which is the “lord” of the aortic rings?

Switch back: Using the pulmonary autograft to replace the aortic valve after arterial switch operation Mark G. Hazekamp, MD, PhDa, Paul H. Schoof, MDa,

A fate worse than death Jennifer S. Lawton, MD

Disproportionate enlargement of the pulmonary autograft in the aortic position in the growing pig Paul H. Schoof, MDa, Mark G. Hazekamp, MD, PhDa, Gijs.

Increase in size of the pulmonary autograft after the ross operation in children: Growth or dilation? Laszlo Solymar, MD, PhD, Göran Südow, MD, Daniel.

Midterm Assessment of the Reconstructed Arteries After the Arterial Switch Operation Thierry Bové, MD, Frederik De Meulder, MD, Guy Vandenplas, MD, Katya.

Surgical Treatment in a Case of Cogan's Syndrome Complicated With Proximal Aortic Vasculitis Mehmet Kaya, MD, Korhan Erkanlı, MD, Furkan Kılınç, MD,

Shirin Lalezari, MD, Edris A. F. Mahtab, PhD, Margot M

What is the best material for extracardiac Fontan operation?

Ralph S. Mosca, MD The Journal of Thoracic and Cardiovascular Surgery

Spiral arterial switch operation in transposition of the great arteries Ing-Sh Chiu, MD, PhD, MDiva, Jou-Kou Wang, MD, PhDb, Mei-Hwan Wu, MD, PhDb The.

Surgical Management of Aortopulmonary Window

Riccardo Codecasa, MD, Massimo A

Long-term results of heart transplantation in patients older than 60 years Philippe Demers, MD, MSc, FRCSC, Susan Moffatt, MD, PhD, FRCSC, Philip E Oyer,

Toward a more rational approach in treating type B aortic dissection

Junaid Haroon, MD, Subroto Paul, MD, MPH

Inflammatory ascending aortic disease: Perspectives from pathology

Ross T. Lyon, M. D. , Arthur Runyon-Hass, Ph. D. , Harry R. Davis, Ph

Preoperative PFTs: The answer is blowing in the wind

What surgical improvements are needed to prove that anatomic repair is superior to physiologic repair in the majority of patients with corrected transposition.

The significance of pulmonary annulus size in the surgical management of transposition of the great arteries with ventricular septal defect and pulmonary.

Descending thoracic and thoracoabdominal aortic aneurysms: “Busted”

Presentation transcript:

Pulmonary artery remodeling in transposition of the great arteries: relevance for neoaortic root dilatation Shirin Lalezari, MD, Mark G Hazekamp, MD, PhD, Margot M Bartelings, MD, PhD, Paul H Schoof, MD, PhD, Adriana C Gittenberger-de Groot, PhD The Journal of Thoracic and Cardiovascular Surgery Volume 126, Issue 4, Pages 1053-1060 (October 2003) DOI: 10.1016/S0022-5223(03)00971-1

Figure 1 Example of a specimen with transposition of the great arteries with the squares representing the sample area. The samples in normal heart specimens were removed at the same location. Aortic (Ao) vessel wall; pulmonary artery (PA) vessel wall; aortic sinus (AoS); PA sinus (PAS). The Journal of Thoracic and Cardiovascular Surgery 2003 126, 1053-1060DOI: (10.1016/S0022-5223(03)00971-1)

Figure 5 The trend between age and actin-negative area in normal aorta and PA vessel wall and sinuses, and in aorta and PA vessel wall and sinuses in TGA. The normal aorta and PA lose a small but not substantial amount of actin with increasing age. The aorta in TGA shows behavior more like normal vessels with increasing age. The PA in TGA shows a very clear trend in loss of actin-positive smooth muscle cells as the patient grows older. The Journal of Thoracic and Cardiovascular Surgery 2003 126, 1053-1060DOI: (10.1016/S0022-5223(03)00971-1)

Figure 2 Resorcin-fuchsin staining of the vessel wall in normal hearts and hearts with TGA. a, b, Case 3; c, d, case 9; e, f, case 14 (Table 2). N, Normal heart; L, luminal side of the vessel. The Journal of Thoracic and Cardiovascular Surgery 2003 126, 1053-1060DOI: (10.1016/S0022-5223(03)00971-1)

Figure 3 a-d, All figures showing anti-α-smooth muscle actin (1A4) staining of the vessel wall of normal hearts and hearts with TGA in the early group. a, b, Case 1; c, d, case 8; e, j, 1A4 staining of the vessel wall of normal hearts and hearts with TGA in different age groups; e, f, case 9; g, h, case 15; i, j, case 18 (Table 3). ▶, Border between media and adventitia; →, thickness of nonstained intima and media. The Journal of Thoracic and Cardiovascular Surgery 2003 126, 1053-1060DOI: (10.1016/S0022-5223(03)00971-1)

Figure 3 a-d, All figures showing anti-α-smooth muscle actin (1A4) staining of the vessel wall of normal hearts and hearts with TGA in the early group. a, b, Case 1; c, d, case 8; e, j, 1A4 staining of the vessel wall of normal hearts and hearts with TGA in different age groups; e, f, case 9; g, h, case 15; i, j, case 18 (Table 3). ▶, Border between media and adventitia; →, thickness of nonstained intima and media. The Journal of Thoracic and Cardiovascular Surgery 2003 126, 1053-1060DOI: (10.1016/S0022-5223(03)00971-1)

Figure 4 a, b, 1A4 staining of the aortic and PAS in the late TGA group (case 18, Table 3). c, The same PAS, stained with α-SM22. d, The PAS stained with calponin. The Journal of Thoracic and Cardiovascular Surgery 2003 126, 1053-1060DOI: (10.1016/S0022-5223(03)00971-1)