Coagulation, fibrinolysis, and platelet activation in patients undergoing open and endovascular repair of abdominal aortic aneurysm Robert S.M. Davies,

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Presentation transcript:

Coagulation, fibrinolysis, and platelet activation in patients undergoing open and endovascular repair of abdominal aortic aneurysm Robert S.M. Davies, MBChB, MMEd, MRCS, Mohamed Abdelhamid, MRCS, Michael L. Wall, MBChB, MRCS, Rajiv K. Vohra, PhD, FRCS, Andrew W. Bradbury, BSc, MBA, MD, FRCSEd, Donald J. Adam, MD, FRCSEd Journal of Vascular Surgery Volume 54, Issue 3, Pages 865-878 (September 2011) DOI: 10.1016/j.jvs.2011.04.010 Copyright © 2011 Society for Vascular Surgery Terms and Conditions

Fig 1 Coagulation cascade. Biomarkers described in the review are highlighted in red. APC, Activated protein C; APC-PCI, activated protein C-protein C inhibitor complex; ATIII, antithrombin III; F1+2, prothrombin fragments 1 and 2; FM-F, fibrin monomer-fibrinogen complex; Plt, platelets; PS, proteins; SP-selectin, soluble P-selectin; TF, tissue factor; TM-IIa, thrombo-modulin-thrombin complex; TAT, thrombin-antithrombin complex; vWF, von Willebrand factor. Journal of Vascular Surgery 2011 54, 865-878DOI: (10.1016/j.jvs.2011.04.010) Copyright © 2011 Society for Vascular Surgery Terms and Conditions

Fig 2 Diagrammatic representation of the fibrinolytic pathway. Biomarkers described in the review are highlighted in red. FDP, Fibrinogen degradation product; PAI-1, plasminogen activator inhibitor type-1; PIC, plasmin inhibitor complex; tPA, tissue plasminogen activator. Journal of Vascular Surgery 2011 54, 865-878DOI: (10.1016/j.jvs.2011.04.010) Copyright © 2011 Society for Vascular Surgery Terms and Conditions