68-year-old patient with memory impairment

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Presentation transcript:

68-year-old patient with memory impairment Teaching Neuroimages Neurology Resident and Fellow Section © 2018 American Academy of Neurology

Vignette A right-handed 68-year-old man presented with acute-onset memory impairment. Before the event, he was doing well in his daily life. He had a history of hypertension. His verbal memory functions exhibited significant impairments. Kang Min Park, et al. © 2018 American Academy of Neurology

Imaging Kang Min Park, et al. A B C D Figure 1. Brain MRI (left) Diffusion-weighted (A), affarent diffusion coefficient (B), and T2-weighted (C, D) images showing an ischemic infarct in the left mammillary body (arrows). Figure 2. Brain CT angiography (right) This figure shows focal stenosis of the bilateral posterior cerebral arteries (arrows). Kang Min Park, et al. © 2018 American Academy of Neurology

Isolated mammillary body infarction presenting with memory impairment A brain MRI revealed an acute infarction in the left mammillary body. The mammillary bodies are part of the Papez circuit, which is involved in memory consolidation and emotional control. Reference 1. Vann SD, Nelson AJ. The mammillary bodies and memory: more than a hippocampal relay. Prog Brain Res 2015;219:163-185. Kang Min Park, et al. © 2018 American Academy of Neurology