Exuberant Positive Patch Test to Abacavir in a Patient with the HLA-B

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Presentation transcript:

Exuberant Positive Patch Test to Abacavir in a Patient with the HLA-B Exuberant Positive Patch Test to Abacavir in a Patient with the HLA-B*5701 Haplotype Sarah Micozzi, MD, Patricia Rojas, MD, Abdonias Rodriguez-Gamboa, MD, Manuel De Barrio, MD The Journal of Allergy and Clinical Immunology: In Practice Volume 3, Issue 6, Pages 965-967 (November 2015) DOI: 10.1016/j.jaip.2015.05.004 Copyright © 2015 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Figure 1 Patch test reading on day 2. The Journal of Allergy and Clinical Immunology: In Practice 2015 3, 965-967DOI: (10.1016/j.jaip.2015.05.004) Copyright © 2015 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Figure 2 Patch test reading on day 4. The Journal of Allergy and Clinical Immunology: In Practice 2015 3, 965-967DOI: (10.1016/j.jaip.2015.05.004) Copyright © 2015 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Figure 3 Patch reading on day 7. The Journal of Allergy and Clinical Immunology: In Practice 2015 3, 965-967DOI: (10.1016/j.jaip.2015.05.004) Copyright © 2015 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Figure 4 The pictures show necrosis of dermal and epidermal tissue (up arrow in A), with a central acute folliculitis area and an inflammatory infiltrate (lower arrow in A), perivascular lymphocytes and some eosinophils (arrow in B) without vasculitis characteristics. The rest of epidermis does not show any type of alteration. The Journal of Allergy and Clinical Immunology: In Practice 2015 3, 965-967DOI: (10.1016/j.jaip.2015.05.004) Copyright © 2015 American Academy of Allergy, Asthma & Immunology Terms and Conditions