Aleksandra Deczkowska, Michal Schwartz  Immunity 

Slides:



Advertisements
Similar presentations
Maintaining Cell Identity through Global Control of Genomic Organization Gioacchino Natoli Immunity Volume 33, Issue 1, Pages (July 2010) DOI: /j.immuni
Advertisements

The Pathobiology of Vascular Dementia Costantino Iadecola Neuron Volume 80, Issue 4, Pages (November 2013) DOI: /j.neuron Copyright.
The Transcription Factor Foxo1 Controls Central-Memory CD8+ T Cell Responses to Infection Myoungjoo V. Kim, Weiming Ouyang, Will Liao, Michael Q. Zhang,
Human Epidermal Langerhans Cells Maintain Immune Homeostasis in Skin by Activating Skin Resident Regulatory T Cells Julien Seneschal, Rachael A. Clark,
Neuronal Cell Types and Connectivity: Lessons from the Retina H. Sebastian Seung, Uygar Sümbül Neuron Volume 83, Issue 6, Pages (September 2014)
Identification and characterization of leukemia stem cells in murine MLL-AF9 acute myeloid leukemia Tim C.P. Somervaille, Michael L. Cleary Cancer Cell.
Human Brown Adipose Tissue Sven Enerbäck Cell Metabolism Volume 11, Issue 4, Pages (April 2010) DOI: /j.cmet Copyright © 2010.
Molecular Motors in Neurons: Transport Mechanisms and Roles in Brain Function, Development, and Disease Nobutaka Hirokawa, Shinsuke Niwa, Yosuke Tanaka.
Lung Airway-Surveilling CXCR3hi Memory CD8+ T Cells Are Critical for Protection against Influenza A Virus Bram Slütter, Lecia L. Pewe, Susan M. Kaech,
Mechanisms of Age-Related Macular Degeneration Jayakrishna Ambati, Benjamin J. Fowler Neuron Volume 75, Issue 1, Pages (July 2012) DOI: /j.neuron
A Death Notice for In-Vitro-Generated GM-CSF Dendritic Cells?
“Toll”-erance in the Skin
Lymphatics as a New Active Player in Reverse Cholesterol Transport
IL-22 Gets to the Stem of Colorectal Cancer
Human-Hemato-Lymphoid-System Mice: Opportunities and Challenges
Interferons Coordinate a Multifaceted Defense
Act1, Scene Brain: Astrocytes Play a Lead Role
Protein Networks in Alzheimer’s Disease
Erythropoietin Surprises: An Immune Saga
Bipotent or Oligopotent? A Macrophage and DC Progenitor Revisited
Upgrading from iMac to iMicro
The Birds, the Bees, and Innate Immunity
Volume 29, Issue 5, Pages (November 2008)
Chronic Infections Capture Little Attention of the Masses
Autophagy: Paying Charon's Toll
Double Duty for CCL21 in Dendritic Cell Trafficking
GM-CSF: From Growth Factor to Central Mediator of Tissue Inflammation
Fibrinogen in the Nervous System: Glia Beware
PU.1 Takes Control of the Dendritic Cell Lineage
HIV and Tfh Cells: Circulating New Ideas to Identify and Protect
CNS Injury: IL-33 Sounds the Alarm
Thymic Selection: To Thine Own Self Be True
Understanding Spontaneous Conversion: The Case of the Ly6C− Monocyte
A Local Role for CD103+ Dendritic Cells in Atherosclerosis
Fungi Take Control of Lymphocyte Recirculation
Th17 Cells Require You to Chew before You Swallow
Commanding CNS Invasion: GM-CSF
Amyloid Cascade into Clarity
“The Very Pulse of the Machine”: The Tuberculous Granuloma in Motion
Interleukin-17 Kick-Starts T Helper 1 Cell Differentiation
Chronic Infections Capture Little Attention of the Masses
Erythropoietin Surprises: An Immune Saga
Volume 64, Issue 1, Pages (October 2009)
A New Link between γδ T Cells and Myeloid Cells in Malaria?
Wait, Wait … OK Now Go In: iNKT Cells Resolve Liver Inflammation
Myeloid Cells in the Central Nervous System
A Tale of Two Genes: Microglial Apoe and Trem2
A Death Notice for In-Vitro-Generated GM-CSF Dendritic Cells?
A Prescription for Human Immunology
A New Role for Glia in Leptin Action and Energy Balance
Double Duty for CCL21 in Dendritic Cell Trafficking
Infected Cells Call Their Killers to the Scene of the Crime
Dorothy P. Schafer, Beth Stevens  Immunity 
GM-CSF: From Growth Factor to Central Mediator of Tissue Inflammation
Michele De Palma, Rakesh K. Jain  Immunity 
Microglia: You’ll Never Walk Alone!
MicroRNA-155 Function in B Cells
IL-10 and Macrophages Orchestrate Gut Homeostasis
Volume 35, Issue 6, Pages (December 2011)
Inflammation 2010: New Adventures of an Old Flame
Sachin P. Gadani, James T. Walsh, John R. Lukens, Jonathan Kipnis 
Copyright © 2013 Elsevier Inc. All rights reserved.
Homegrown Macrophages
Recycling Endosomes and TLR Signaling— The Rab11 GTPase Leads the Way
Even Neurons Are Excited by Th17 Cells
t Testing the Immune System
There's a Time and a Place for MYCN
At 17, In-10's Passion Need Not Inflame
Microglia: You’ll Never Walk Alone!
Notch 1 Keeps Pro-T cells on Track
Presentation transcript:

Making Ends Meet: Myeloid Cells Catalyze Blood Vessel Repair in the Brain  Aleksandra Deczkowska, Michal Schwartz  Immunity  Volume 44, Issue 5, Pages 1081-1083 (May 2016) DOI: 10.1016/j.immuni.2016.04.024 Copyright © 2016 Elsevier Inc. Terms and Conditions

Figure 1 Myeloid Cells’ Roles in Acute CNS Injury Upon rupture of a blood vessel in the brain, the tissue immediately shows signs of stress, e.g., microglia activation and neuronal death. Under these conditions, myeloid cells (both microglia and infiltrating, monocyte-derived macrophages) fulfill a range of protective roles, including phagocytosis of cellular debris, release of neuroprotective factors, and, as now reported by Liu et al. (2016), directly supporting re-ligation of ruptured blood vessels by adhesion and mechanical traction. Immunity 2016 44, 1081-1083DOI: (10.1016/j.immuni.2016.04.024) Copyright © 2016 Elsevier Inc. Terms and Conditions