Epileptic prodromes: Are they nonconvulsive status epilepticus?

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Epileptic prodromes: Are they nonconvulsive status epilepticus? Jørgen Alving, Sándor Beniczky  Seizure - European Journal of Epilepsy  Volume 22, Issue 7, Pages 522-527 (September 2013) DOI: 10.1016/j.seizure.2013.03.013 Copyright © 2013 British Epilepsy Association Terms and Conditions

Fig. 1 Generalised, 1.5–2Hz paroxysmal activity, interspersed with runs of 4–5Hz “notched” theta, mainly bifrontal, and without any focal traits (A). The paroxysmal activity did not respond to intravenous VPA (2200mg); 10min later, DZP (5mg) was given i.v. and the EEG normalised within 30s (B). EEG is showed here in longitudinal bipolar montage. Supplementary material 2 shows the same EEG segments in common average montage. The patient has symptomatic focal epilepsy (left frontal meningioma). Seizure - European Journal of Epilepsy 2013 22, 522-527DOI: (10.1016/j.seizure.2013.03.013) Copyright © 2013 British Epilepsy Association Terms and Conditions

Fig. 2 Continuous, diffuse 5–7Hz activity, with occasional sharp-waves in the left and right posterior quadrant (A). Eye closing/opening induced no alteration. Injection of 1mg clonazepam i.v. improved the background activity considerably within about 90s (B), in parallel with a good clinical response (symptoms subsided). EEG is showed here in longitudinal bipolar montage. Supplementary material 3 shows the same EEG segments in common average montage. The patient was diagnosed with cryptogenic generalised epilepsy. Seizure - European Journal of Epilepsy 2013 22, 522-527DOI: (10.1016/j.seizure.2013.03.013) Copyright © 2013 British Epilepsy Association Terms and Conditions

Fig. 3 Continuous rhythmic 1.5–2.5Hz spike-and-slow-wave paroxysms, lasting for up to 45min; this activity was almost always fronto-temporal with shifting side preponderance, or bifrontal synchronous (A). EEG became normalised after cessation of symptoms (B). EEG is showed here in longitudinal bipolar montage. Supplementary material 4 shows the same EEG segments in common average montage. The patient has symptomatic focal epilepsy (bilateral mesial temporal sclerosis). Seizure - European Journal of Epilepsy 2013 22, 522-527DOI: (10.1016/j.seizure.2013.03.013) Copyright © 2013 British Epilepsy Association Terms and Conditions