Gastric Cancer and the High Combination Prevalence of Host Cytokine Genotypes and Helicobacter pylori in Honduras  Douglas R. Morgan, Ricardo L. Dominguez,

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Gastric Cancer and the High Combination Prevalence of Host Cytokine Genotypes and Helicobacter pylori in Honduras  Douglas R. Morgan, Ricardo L. Dominguez, Temitope O. Keku, Paris E. Heidt, Christopher F. Martin, Joseph A. Galanko, Oluwaseun A. Omofoye, Robert S. Sandler  Clinical Gastroenterology and Hepatology  Volume 4, Issue 9, Pages 1103-1111 (September 2006) DOI: 10.1016/j.cgh.2006.05.025 Copyright © 2006 American Gastroenterological Association Terms and Conditions

Figure 1 Correlation between population gastric cancer incidence and the CPI. The CPI is defined as the product of the H pylori prevalence and the IL-1β-511T+ prevalence, expressed as a percentage, in the population of interest. A significant association is noted between the country-specific CPI and gastric cancer incidence for 16 populations (P = .0057). Gastric cancer incidence, combined for males and females, is obtained from the International Agency for Research on Cancer. Gu, Guangdong; Sx, Shanxi; Ji, Jiangsu; Sh, Shangdong; N, northern Italy; S, southern Italy. •, Country; —, fitted values (F = 10.60, P = .0057). Clinical Gastroenterology and Hepatology 2006 4, 1103-1111DOI: (10.1016/j.cgh.2006.05.025) Copyright © 2006 American Gastroenterological Association Terms and Conditions