Characteristics of advanced fibrosis in usual interstitial pneumonia of idiopathic pulmonary fibrosis include a subpleural distribution of fibrosis (A,

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History : 52-year-old male presented with a left testicular mass. An initial chest radiograph was performed, followed by a CT. Question : What are the.

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Date of download: 9/17/2016 Copyright © 2016 American Medical Association. All rights reserved. From: Demystifying Idiopathic Interstitial Pneumonia Arch.

Volume 134, Issue 1, Pages (July 2008)

Kaplan-Meier survival curves by frequency of exacerbations in patients with COPD: group A, patients with no acute exacerbations of COPD; group B, patients.

Idiopathic Pulmonary Fibrosis: Current Concepts

Stratified mucinous intraepithelial lesion in which stratified epithelium resembling cervical intraepithelial neoplasia contains abundant mucin globules.

(A) Vascular endothelial growth factor D (VEGF-D) staining in luminal ductal cells with occasional staining in myoepithelial cells of normal breast. (A)

Pathological alterations in idiopathic pulmonary fibrosis (IPF).

EEG maximal power frequency and relative power frequency distribution from 12 surface electrodes (horizontal axis) in children with (open circles) and.

Changes in high-resolution computed tomography (HRCT) pattern over time. a) Idiopathic pulmonary fibrosis (IPF), increased specificity over time. Changes.

Usual Interstitial Pneumonia Complicating Dyskeratosis Congenita

Catecholamines and metabolites expressed for each mole of creatinine in single voided urine specimens on one preoperative (day 0) and four postoperative.

Demonstration of Helicobacter pylori by the four staining methods: (A) modified Giemsa, (B) anti-H pylori antibody immunostain, (C) modified McMullen's.

(A,B) mRNA in situ hybridisation (ISH) with Epstein–Barr virus-encoded small RNA-1 probe in a case of Hodgkin’s lymphoma focally affecting the bone marrow.

(A) The two tumours at the end of the ascending and transverse colon are indicated by the arrows. (A) The two tumours at the end of the ascending and transverse.

Pilomatricoma: (A) a multilobulated mass in fibrous stroma reaching the subcutis; (B) basaloid and ghost cells; (C) mitoses in an early lesion; and (D)

(A–F) Hairy-cell leukaemia, haematoxylin and eosin (H&E) staining (A) ×40; (B) ×200; (C) TRAP, ×200; (D) CD25, ×200; (E) DBA44, ×200; (F) CD20, ×200.

The figure shows representative tissue from multiple gastric biopsies in which the expression of parathyroid hormone related peptide (PTHrP) was investigated.

(A) Histiocytes of duct ectasia, where in the absence of an intact duct, the histiocytic population can resemble the tumour cells of histiocytoid breast.

Idiopathic Pulmonary Fibrosis: Evolving Concepts

Case 1. Case 1. (A) Low power photomicrograph of renal medulla showing a poorly formed granuloma with several disrupted and destroyed renal tubules within.

Frozen sections of (A) fetal intestine, (B) tonsil, and (C) mantle cell lymphoma, stained using anti-CD3 (immunoperoxidase; brown) followed by anti-CD5.

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Representative images of immunohistochemical staining of discoidin domain receptor (DDR)2 in interstitial lung disease (ILD) other than idiopathic pulmonary.

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Silicatosis. Silicatosis. Similar to sarcoidosis in distribution, the nodules of silicate disease can be distinguished by the common occurrence of dark.

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Axial computed tomography (CT) images a) at baseline and b) at a 12-month follow-up scan, in a patient with idiopathic pulmonary fibrosis (IPF). b) Note.

High-power view of high-grade dysplasia with intramucosal adenocarcinoma. High-power view of high-grade dysplasia with intramucosal adenocarcinoma. The.

The Histopathology of IPF

By immunohistochemistry, 50% of inflammatory myofibroblastic tumours show expression of ALK, which correlates with ALK gene rearrangement. By immunohistochemistry,

Young people drink significantly less frequently than older people (A), but drink significantly more on each drinking day (panel B). Young people drink.

Percentage of medical laboratory assistants to medical laboratory scientific officers for each of the main disciplines within pathology:(A) biochemistry,

Non-medical productivity in microbiology: requests for each non-medical/non-clinical scientist whole time equivalent—that is, for each whole time equivalent.

Evaluation of acute symptoms

(A–D) Atypical paracortical hyperplasia pattern and (E, F) burnt out histiocytic pattern of lymphadenopathy in adult onset Still’s disease (AOSD). (A–D)

Area under the receiver operating curve showing 0

Relative fibroblast proliferation induced by bronchoalveolar lavage fluid obtained from infants who progressed to chronic lung disease of prematurity (CLD),

Area under the receiver operating curve showing 0

Area under the receiver operating curve showing 0

Analysis of PD-L1 tumour-cell membrane staining concordance between PD-L1 immunohistochemistry 22C3 and 28-8 assays across all matched tumour biopsies.

Pairwise comparison for lung cancer or unspecified cancer diagnosis for most frequent biopsy sites (lung or lymph node). Pairwise comparison for lung cancer.

Transbronchial cryobiopsy (TBCx)

PAX8 (mAb) immunohistochemistry in POMTs, eMOMCs and ePMCs.

Pie chart demonstrating relative proportion of specialists within the multidisciplinary sample—there were six consultant surgeons, six inflammatory bowel.

Volume 155, Issue 4, Pages e91-e96 (April 2019)

Computer-aided Quantification of Pulmonary Fibrosis in Patients with Lung Cancer: Relationship to Disease-free Survival Of 217 patients with lung cancer,

Area under the receiver operating curve showing 0

A) Small pulmonary arteries within a fibrotic area (usual interstitial pneumonia lung). a) Small pulmonary arteries within a fibrotic area (usual interstitial.

Sensitivity and specificity plots of human epididymis protein 4 (HE4) (A and B, respectively) and carbohydrate antigen 125 (CA-125) (C and D, respectively)

RNAi screening formats.

Usual interstitial pneumonia pattern in two patients with idiopathic pulmonary fibrosis. a) At low magnification, subpleural/paraseptal scars obscuring.

Distribution of NEWS in the community by service

Kaplan-Meier survival curves by frequency of exacerbations in patients with COPD: group A, patients with no acute exacerbations of COPD; group B, patients.

(A) Parathyroid imprint cytology showing the typical evenly stained round nuclei (May-Grünwald-Giemsa stain). (A) Parathyroid imprint cytology showing.

Chromatogram from the ion exchange high performance liquid chromatography Bio-Rad Variant II using the high resolution β thalassaemia programme in a patient.

(A) Fibrosis of the submucosa with replacement of the muscularis mucosae. (A) Fibrosis of the submucosa with replacement of the muscularis mucosae. The.

A representative case of coexisting granulomatous inflammation (black arrowheads) and squamous cell carcinoma (white arrows) in a lobectomy specimen in.

Low grade cervical glandular intraepithelial neoplasia in which there is mild nuclear atypia and easily identifiable mitotic figures and apoptotic bodies.

Relationship of the internal jugular vein diameter to various angles of Trendelenburg tilt. Relationship of the internal jugular vein diameter to various.

(A and B) Low-grade serrated dysplasia, on the other hand, is characterised by ovoid enlarged nuclei, vesicular dispersed chromatin and occasional mitoses.

Presentation transcript:

Characteristics of advanced fibrosis in usual interstitial pneumonia of idiopathic pulmonary fibrosis include a subpleural distribution of fibrosis (A, 20×, H&E), relative frequency of fibroblast foci (arrows) and relative absence of any significant inflammatory cell infiltrate (B, 400×, H&E), smooth muscle proliferation in the subpleural scars (asterisk) (C, 40×, H&E), and the frequent occurrence of microscopic honeycomb remodelling (D, 20×, H&E). Characteristics of advanced fibrosis in usual interstitial pneumonia of idiopathic pulmonary fibrosis include a subpleural distribution of fibrosis (A, 20×, H&E), relative frequency of fibroblast foci (arrows) and relative absence of any significant inflammatory cell infiltrate (B, 400×, H&E), smooth muscle proliferation in the subpleural scars (asterisk) (C, 40×, H&E), and the frequent occurrence of microscopic honeycomb remodelling (D, 20×, H&E). Maxwell Smith et al. J Clin Pathol 2013;66:896-903 Copyright © by the BMJ Publishing Group Ltd & Association of Clinical Pathologists. All rights reserved.