A proposed treatment model for the decision-making process when choosing between cetuximab continuation vs rechallenge. aTypically patients with left-sided,

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Presentation transcript:

A proposed treatment model for the decision-making process when choosing between cetuximab continuation vs rechallenge. aTypically patients with left-sided, RAS wt mCRC or those with right-sided, RAS wt mCRC in need of rapid tumour shrinkage. bBy liquid biopsy. cOther evidence-based biomarkers can also be included in the panel of tests when feasible. A proposed treatment model for the decision-making process when choosing between cetuximab continuation vs rechallenge. aTypically patients with left-sided, RAS wt mCRC or those with right-sided, RAS wt mCRC in need of rapid tumour shrinkage. bBy liquid biopsy. cOther evidence-based biomarkers can also be included in the panel of tests when feasible. EGFR, epidermal growth factor receptor; FOLFIRI, 5-fluorouracil, leucovorin and irinotecan; FOLFOX, 5-fluorouracil, leucovorin and oxaliplatin; mut, mutant; PD, progressive disease; wt, wild-type. Richard M Goldberg et al. ESMO Open 2018;3:e000353 Copyright © European Society for Medical Oncology. All rights reserved.