Chloride Channel Function

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Chloride Channel Function Filippo Mancia, Lawrence Shapiro Structure Volume 10, Issue 3, Pages 283-284 (March 2002) DOI: 10.1016/S0969-2126(02)00735-9

Figure 1 Structure of the S. typhimerium ClC Channel (A) Ribbon representation of the dimer shown from the extracellular side. The two monomers of the channel are shown in red and blue, and the bound chloride ions are shown as green spheres. (B) View from within the membrane plane, with the extracellular side above. (C) Topology diagram of the monomer, showing the pseudosymmetrical halves in blue and green. Regions forming the selectivity filter are shown in red. (D) Monomeric subunit, viewed from within the plane of the membrane, colored as in (C), with the chloride ion shown as a red sphere (modified from Dutzler et al., 2002). Structure 2002 10, 283-284DOI: (10.1016/S0969-2126(02)00735-9)