Volume 46, Issue 2, Pages 247-253 (August 2004) P2X3-Immunoreactive Nerve Fibres in Neurogenic Detrusor Overactivity and the Effect of Intravesical Resiniferatoxin  Ciaran M Brady, Apostolos Apostolidis, Yiangos Yiangou, Preston A Baecker, Anthony P Ford, Alex Freeman, Thomas S Jacques, Clare J Fowler, Praveen Anand  European Urology  Volume 46, Issue 2, Pages 247-253 (August 2004) DOI: 10.1016/j.eururo.2003.12.017

Fig. 1 Significant increase of mean density of P2X3-IR suburothelial nerve fibres in patients with NDO compared to controls (∗p=0.014). European Urology 2004 46, 247-253DOI: (10.1016/j.eururo.2003.12.017)

Fig. 2 Suburothelial nerve fibres stained for P2X3 in a biopsy from a NDO patient who responded to RTX, before (left) and after treatment (right). European Urology 2004 46, 247-253DOI: (10.1016/j.eururo.2003.12.017)

Fig. 3 A significant reduction (∗p=0.032) in the mean density of P2X3-IR suburothelial fibres was noticed following treatment in the 5 patients who responded to RTX, to values found in control tissues (a). No significant change in mean P2X3 suburothelial immunoreactivity was observed in non-responders (b). European Urology 2004 46, 247-253DOI: (10.1016/j.eururo.2003.12.017)